Last update 25 Sep 2025

AT1R x HMGCR x L-type calcium channel

Basic Info

Related Targets
AT1RHMGCRL-type calcium channel

Related

2
Drugs associated with AT1R x HMGCR x L-type calcium channel
Telmisartan/Rosuvastatin Calcium/Amlodipine Besylate/Ezetimibe
Target
AT1R x HMGCR x L-type calcium channel x NPC1L1
Mechanism
AT1R antagonists [+4]
Active Org.
Chong Kun Dang Pharmaceutical Corp.Chong Kun Dang Pharmaceutical Corp.
Originator Org.
Chong Kun Dang Pharmaceutical Corp.Chong Kun Dang Pharmaceutical Corp.
Active Indication
Dyslipidemias [+3]
Inactive Indication-
Drug Highest PhaseApproved
First Approval Ctry. / Loc.
South Korea
First Approval Date21 Mar 2025
Losartan Potassium/Ezetimibe/Amlodipine Besylate/Rosuvastatin Calcium
Target
AT1R x HMGCR x L-type calcium channel x NPC1L1
Mechanism
AT1R antagonists [+4]
Active Org.
Hanmi Pharmaceutical Co., Ltd.Hanmi Pharmaceutical Co., Ltd.
Originator Org.
Hanmi Pharmaceutical Co., Ltd.Hanmi Pharmaceutical Co., Ltd.
Active Indication
Hypertension [+1]
Inactive Indication-
Drug Highest PhaseApproved
First Approval Ctry. / Loc.
South Korea
First Approval Date09 Nov 2020
16
Clinical Trials associated with AT1R x HMGCR x L-type calcium channel
KCT0004273
/ RecruitingPhase 4IIT
A Multi-center, Randomized, Parallel Phase IV Clinical Trial to Evaluate the Efficacy and Safety of Triple therapy of Telmisartan/Amlodipine/Rosuvastatin in Patients with Dyslipidemia and Hypertension
NCT03707899
/ CompletedPhase 1
An Open Label, Randomized, Single-dose, 4-period Cross-over Study to Compare the Pharmacokinetics and Safety Following Administration of JLP-1401 and Co-administration of Telmisartan/Amlodipine and Rosuvastatin in Healthy Adult Volunteers
KCT0003475
/ CompletedPhase 3
A multi-center, Randomized, Double-blind, Parallel Phase III Clinical Trial to Evaluate the efficacy and safety of Triple combination therapy of Amlodipine/Valsartan/Rosuvastatin in Paients with Dyslipidemia and Hypertension
100 Clinical Results associated with AT1R x HMGCR x L-type calcium channel
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100 Translational Medicine associated with AT1R x HMGCR x L-type calcium channel
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0 Patents (Medical) associated with AT1R x HMGCR x L-type calcium channel
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