Last update 01 Nov 2024

CXCR2

Basic Info

Synonyms
白细胞介素-8B受体, C-X-C chemokine receptor type 2, C-X-C motif chemokine receptor 2
+ [13]
Introduction
Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor (PubMed:1891716). Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system (PubMed:8662698). Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.

Analysis

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