RANKL inhibitors are drugs that target the RANKL protein, crucial in bone metabolism. The future sees potential applications in treating bone-related disorders and certain cancers.
PD-1 inhibitors are drugs that target the PD-1 protein, crucial for regulating immune responses. The future of PD-1 inhibitors is promising, with potential applications in treating various types of cancer.
Renin inhibitors are drugs that target the enzyme renin, crucial in regulating blood pressure. The future sees potential applications in treating hypertension and other cardiovascular diseases.
PARP inhibitors are drugs targeting the DNA-repairing enzyme PARP1, used in treating ovarian and breast cancer. With ongoing R&D, their future use is expected to expand.
PD-L1 inhibitors can specifically bind to PD-L1 on tumor cells to inhibit its expression, thereby enabling T cells, whose function has been suppressed, to restore their ability to recognize tumor cells.
NTRK fusion is a driving factor in various adult and pediatric cancers, especially in certain rare tumors like infantile fibrosarcoma and secretory breast cancer, where it is highly enriched. Therefore, the future application prospects of NTRK inhibitors in this area are very promising.
PCSK9 inhibitors can significantly reduce LDL-C levels, and the development of related drugs is of great importance for the treatment of cardiovascular diseases.