Beyond the drugs targeting specific pathways like the Activin - ActRII - ActRI pathway, there are other medications being developed for obesity and muscle - wasting disorders.
The discovery of INHBE and ALK7 as potential drug targets has opened up new avenues in the development of therapies for obesity and metabolic disorders.
By conducting in - depth searches in relevant databases, the development of drugs targeting MSTN/GDF8 and bone morphogenetic proteins (BMPs) has been revealed.
Through comprehensive searches in the Patsnap Synapse database, it has been found that the key drugs targeting ActRII mainly consist of fusion proteins and monoclonal antibodies.
The Activin - ActRII - ActRI pathway is a key regulatory pathway in muscle growth and has attracted significant attention in the research of muscle - related diseases and weight - loss therapies.