User-friendly Guide to Find Quetiapine on Synapse

Quetiapine, marketed as SEROQUEL, is an atypical antipsychotic medication developed and produced by AstraZeneca. It was first approved by the US FDA on September 26, 1997, for the treatment of schizophrenia in adults. Quetiapine's mechanism of action is not well understood, but it is believed to be related to its antagonism of dopamine type 2 (D2) and serotonin type 2 (5HT2) receptors. Its active metabolite, norquetiapine, has similar activity at D2 receptors but has greater activity at 5HT2A receptors. Quetiapine is used to treat schizophrenia, bipolar I disorder manic episodes, and bipolar disorder depressive episodes. However, it has potential side effects, such as sedation, weight gain, metabolic changes, and movement disorders. It should only be taken as directed by a healthcare professional. Click on the image below to begin the exploration journey of Quetiapine through the Synapse database!

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