Kurome Therapeutics has received authorization from the FDA to conduct clinical trials for KME-0584, aimed at addressing Acute Myeloid Leukemia (AML) and advanced-stage Myelodysplastic Syndromes (MDS).
Methotrexate, a DHFR-inhibiting drug approved in the US since 1953, is known for treating various conditions such as acute lymphoblastic leukemia, breast cancer, severe psoriasis, and rheumatoid arthritis in both adults and children.
Pregabalin, commonly referred to as Lyrica®, is a well-known anticonvulsant medication, which has found its footing in the treatment of various medical conditions.
Repare Therapeutics Inc. announced the first patient has been treated in their LIONS Phase 1 trial, focusing on RP-1664 – a leading oral inhibitor targeting polo-like kinase 4, intended for solo therapy.
Aripiprazole, sold as Abilify Discmelt®, is an atypical antipsychotic for treating schizophrenia, bipolar disorder, depression, autism-related irritability, and Tourette's syndrome.