Synonyms ADPKD, ADPKD - Autosomal dominant polycystic kidney disease, ADPKD - autosomal dominant polycystic kidney disease + [64] |
Introduction Kidney disorders with autosomal dominant inheritance and characterized by multiple CYSTS in both KIDNEYS with progressive deterioration of renal function. |
Target |
Mechanism Bcr-Abl inhibitors [+1] |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. United States |
First Approval Date04 Sep 2012 |
Target |
Mechanism AVPR2 antagonists |
Active Org. |
Originator Org. |
Inactive Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. United States |
First Approval Date19 May 2009 |
Target |
Mechanism RARα agonists |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. Japan |
First Approval Date11 Apr 2005 |
Start Date01 Jul 2025 |
Sponsor / Collaborator |
Start Date01 May 2025 |
Sponsor / Collaborator [+1] |
Start Date07 Apr 2025 |
Sponsor / Collaborator |