Introduction Syros Pharmaceuticals is a life sciences corporation that specializes in identifying and modifying the factors that regulate gene expression to treat various diseases. The company has developed groundbreaking gene control research and drug discovery capabilities, utilizing a unique platform that integrates disease biology and genomic data. Syros' approach has shown significant potential in oncology, where it aims to address unmet medical needs. |
Disease Domain | Count |
---|---|
Neoplasms | 5 |
Hemic and Lymphatic Diseases | 2 |
Endocrinology and Metabolic Disease | 2 |
Top 5 Drug Type | Count |
---|---|
Small molecule drug | 4 |
Monoclonal antibody | 1 |
Target |
Mechanism RARα agonists |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. JP |
First Approval Date11 Apr 2005 |
Mechanism DNA inhibitors [+5] |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhasePhase 3 |
First Approval Ctry. / Loc.- |
First Approval Date- |
Target |
Mechanism CALR modulators |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication- |
Drug Highest PhasePhase 1 |
First Approval Ctry. / Loc.- |
First Approval Date- |
Start Date14 Sep 2023 |
Sponsor / Collaborator |
Start Date01 Oct 2022 |
Sponsor / Collaborator |
Start Date22 Sep 2021 |
Sponsor / Collaborator |
Drug(Targets) | Indications | Global Highest Phase |
---|---|---|
Tamibarotene ( RARα ) | RARA positive Myelodysplastic Syndrome More | Phase 3 |
Sirolimus/Phenytoin/Methoxsalen/Tyrosine isomer ( DNA x Nav1.1 x Nav1.5 x mTOR ) | Pancreatic Cancer More | Phase 3 |
SY-5609 ( CDK7 ) | Pancreatic Cancer More | Phase 1 |
INCA-033989 ( CALR ) | Neoplasms More | Preclinical |
SY-12882 ( CDK12 ) | Neoplasms More | Preclinical |