Synonyms Alveolitides, Fibrosing, Alveolitis, Fibrosing, Cirrhosis of lung + [60] |
Introduction A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death. |
Target |
Mechanism CSF-1R antagonists |
Active Org. |
Originator Org. |
Active Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. US |
First Approval Date14 Aug 2024 |
Target |
Mechanism IL-13 inhibitors |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. EU [+3] |
First Approval Date16 Nov 2023 |
Target |
Mechanism P2X3 receptor antagonists |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. JP |
First Approval Date20 Jan 2022 |
Start Date30 Sep 2024 |
Sponsor / Collaborator |
Start Date01 Sep 2024 |
Sponsor / Collaborator Endeavor BioMedicines, IncStartup |
Start Date27 Jul 2024 |
Sponsor / Collaborator |