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Last update 08 May 2025

Acute suppurative appendicitis

Last update 08 May 2025

Basic Info

Synonyms

Acute suppurative appendicitis, Acute suppurative appendicitis (diagnosis), Acute suppurative appendicitis (disorder)

+ [1]

Introduction-

Drugs associated with Acute suppurative appendicitis

Changtong Oral Liquid

Target-

Mechanism-

Active Org.

The First Military Medical University of the Chinese People's Liberation Army

[+1]

Originator Org.-

Active Indication

Surgical Adhesion

Inactive Indication

Acute suppurative appendicitis [+5]

Drug Highest PhasePhase 3

First Approval Ctry. / Loc.-

First Approval Date20 Jan 1800

Clinical Trials associated with Acute suppurative appendicitis

NCT06365632

/ Active, not recruitingPhase 2IIT

A Prospective, Randomized, Parallel, Single-blind Clinical Study of the Effectiveness, Tolerability and Safety of the Drug "Anti-spike, Gel, 100 g in Bottles in Package No. 1" Produced by the Republican Unitary Enterprise "Unitekhprom BSU", Belarus, With a Single Intraperitoneal Use After Surgical Interventions in Adult Patients With Acute Phlegmonous Appendicitis

The purpose of the clinical trials is the evaluation of the effectiveness and safety of a single intraperitoneal use of the drug "Antispike, gel, 100 g in a bottle" produced by Unitary Enterprise Unitehprom BSU, Belarus in patients after surgical control of acute phlegmonous appendicitis to prevent abdominal adhesions.

Start Date19 Mar 2025

Sponsor / Collaborator

Unitary Enterprise UNITEHPROM BSU

CTR20170198

/ CompletedPhase 2

常通口服液防治手术后腹膜粘连的有效性和安全性Ⅱ期临床试验

[Translation] Phase II clinical trial on the effectiveness and safety of Changtong oral liquid in preventing and treating postoperative peritoneal adhesions

1.评价常通口服液用于单纯性阑尾炎、急性化脓性阑尾炎、慢性阑尾炎或因子宫肌瘤而行腹式全子宫切除术、腹式子宫次全切术的腹部手术患者术后腹膜粘连的临床防治效果。 2.评价常通口服液用于腹部手术患者术后腹膜粘连的安全性与不良反应。

[Translation]

1. To evaluate the clinical efficacy of Changtong oral liquid in the prevention and treatment of postoperative peritoneal adhesion in patients with simple appendicitis, acute suppurative appendicitis, chronic appendicitis, or abdominal hysterectomy or subtotal abdominal hysterectomy due to uterine fibroids. 2. To evaluate the safety and adverse reactions of Changtong oral liquid in the treatment of postoperative peritoneal adhesion in patients with abdominal surgery.

Start Date07 Oct 2010

Sponsor / Collaborator

The First Military Medical University of the Chinese People's Liberation Army

[+1]

100 Clinical Results associated with Acute suppurative appendicitis

100 Translational Medicine associated with Acute suppurative appendicitis

0 Patents (Medical) associated with Acute suppurative appendicitis

202

Literatures (Medical) associated with Acute suppurative appendicitis

01 Apr 2025·Radiology Case Reports

Double whammy: Acute suppurative appendicitis on top of Meckel's diverticulum

Article

Author: Abdelsalam, Mohamed ; Amir, Hosam ; Basheer, Tibyan ; Hafez, Hadeer

Meckel's diverticulum (MD), a congenital abnormality occurring in 0.3% to 3% of individuals, shares overlapping clinical features with acute appendicitis (AA), a common surgical emergency, making simultaneous presentation diagnostically challenging. An 11-year-old boy presented with right lower abdominal pain, fever, and loss of appetite, exhibiting positive Rovsing and Psoas signs. Elevated inflammatory markers and ultrasound findings suggested acute appendicitis with concurrent Meckel's diverticulitis. Surgery confirmed acute suppurative appendicitis and an inflamed MD, both of which were successfully treated with appendectomy and segmental intestinal resection. The patient had an uneventful recovery and remained well during follow-up. This case highlights the importance of considering MD in pediatric abdominal pain and performing thorough intraoperative assessments to ensure accurate diagnosis and effective treatment.

01 Apr 2025·DEN Open

Appendicitis after endoscopic band ligation for massive ileocecal hemorrhage

Author: Sato, Hiroto ; Ohtaki, Yu ; Toda, Makoto ; Kanno, Takeshi ; Kaizuka, Akira ; Yamamoto, Yu ; Fujishima, Shoichiro ; Shirahata, Nakao ; Ae, Ryusuke

AbstractA 68‐year‐old man was admitted with hematochezia. Emergency computed tomography showed multiple diverticula throughout the colon. Initial colonoscopy on day 2 showed no active bleeding, but massive hematochezia on day 3 led to the performance of an emergency endoscopy. Substantial bleeding in the ileocecal area obscured the visual field, making it challenging to view the area around the bleeding site. Two endoscopic band ligations (EBLs) were applied at the suspected bleeding sites. Hemostasis was achieved without active bleeding after EBL. However, the patient developed lower right abdominal pain and fever (39.4°C) on day 6. Urgent computed tomography revealed appendiceal inflammation, necessitating emergency open ileocecal resection for acute appendicitis. Pathological examination confirmed acute phlegmonous appendicitis, with EBLs noted at the appendiceal orifice and on the anal side. This case illustrates the efficacy of EBL in managing colonic diverticular bleeding. However, it also highlights the risk of appendicitis due to EBL in cases of ileocecal hemorrhage exacerbated by poor visibility due to substantial bleeding. Endoscopists need to consider this rare but important complication when performing EBL in similar situations.

28 Feb 2025·Medicine

Horseshoe appendix: A case report and literature review

Review

Author: Pflieger, Hannah ; Tchikladzé-mérand, Christine

Rationale:Horseshoe appendix is 1 of the rarest types of duplex appendix characterized by 1 appendix having 2 openings at the cecum. Clinically, it is extremely rare and is detected incidentally at surgery. Therefore, accurate and timely diagnosis is important for enhanced prognosis, treatment planning, and optimizing patient outcomes. This case report presents the first case of horseshoe appendix in France.Patient concerns:A French 15-year-old boy, presented to the emergency department with pain in the right iliac fossa that had been worsening for 4 days. Considering his symptoms, abdominal ultrasound, radiological examination, and computed tomography (CT) scan results, an acute appendix was suspected.Diagnoses:Acute appendicitis (AA) with “horseshoe” type appendix.Interventions:Surgical intervention with exploratory laparoscopy was performed immediately.Outcomes:We found a heterogeneous image, partially fluid in the right iliac fossa, measuring approximately 16 × 9 mm, with inflammatory remodeling of the fat upon contact. The radiological examination concluded that complicated AA was suspected. Finally, the pathological report revealed acute suppurative appendicitis with peritoneal reaction.Lessons:Horseshoe appendix is rare. Considering his symptoms, radiological examination, ultrasound, and CT scan results, an acute appendix was suspected. The patient was successfully treated using emergency surgery and antibiotics treatment thanks to further diagnosis via exploratory laparoscopy and pus microbial analysis.

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Acute suppurative appendicitis

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