Focal Infection, Dental

VANCOUVER, BC, Oct. 17, 2022 /PRNewswire/ - Asep Medical Holdings Inc. ("Asep Inc." or the "Company") (CSE: ASEP) (OTCQB: SEPSF) is very pleased to announce that it has signed a Feasibility Study Agreement with the Chinese firm Bohai Biomedical Technology Development Co. Ltd., (Bohai Biomedical). The agreement permits Bohai Biomedical to conduct a feasibility study using Asep Inc.'s proprietary anti-bacterial peptide as an active ingredient. The peptide will be studied as an agent to mitigate and prevent erosive dental biofilm infections in an oral rinse product. The peptide technology has been in-licenced from the University of British Columbia (UBC) to Asep Inc.'s subsidiary, ABT Innovations. The agreement with Bohai Biomedical was signed on October 3, 2022, and the study is set to commence in the coming weeks with several thousand participants. The peptide mouthwash has already undergone testing at the UBC Department of Dentistry under the supervision of Dr. Ya Shen and Dr. Markus Haapasalo in close collaboration with the Asep Inc. team. The preliminary results look promising in fighting difficult-to-treat oral biofilms, which are at the heart of a USD$36.2 billion global dental market.1 "We are firmly aiming at the high-end dental market to both prevent and reverse the growth of oral biofilms that cause havoc with oral health. Bohai Biomedical is an excellent and important partner to enable us to confirm the safety and efficacy of our product," said Dr. Robert E. W. Hancock, Chair and CEO of Asep Inc. and co-discoverer of the peptide technology. "This provides us with exciting opportunities in the Chinese dental market that is proposed to be worth USD$17 billion by 2026,2" said Fadia Saad, Chief Business Officer of Asep Inc. "Oral rinses provide a fast-track path to profitability in this arena since they enable a non-FDA route to commercialization." ABOUT BOHAI BIOMEDICAL Bohai Biomedical bohaibiomedical.com/en/ is a Chinese medical technology testing company in Hebei Province. Established in 2010, the company uses its patented proteolysis targeting chimera (PROTAC) technology platform to conduct vital clinical research for both the Chinese and global markets. The company offers a highly-skilled team and advanced testing in their modern facilities, including drug design, molecular biology, cell screening, chemical analysis and instrument analysis services. ABOUT ASEP MEDICAL HOLDINGS INC. Asep Medical Inc. (asepmedical.com) is dedicated to addressing antibiotic failure by developing novel solutions for significant unmet medical needs. The Company is a consolidation of two existing private companies (Sepset Biosciences Inc. and ABT Innovations Inc.) that are both in the advanced development of both proprietary diagnostic tools, enabling the early and timely identification of severe sepsis as well as broad-spectrum therapeutic agents to address multidrug-resistant biofilm infections. ABT Innovations Inc.'s (abtinnovations.ca) peptide technology covers a broad range of therapeutic applications, including bacterial biofilm infections (medical device infections, chronic infections, lung, bladder, wound, dental, skin, ear-nose and throat, sinusitis, orthopaedic, etc.), anti-inflammatories, anti-infective immune-modulators and vaccine adjuvants. The company is in the pre-clinical development phase with promising data. Sepset Biosciences Inc. (sepset.ca) is developing a diagnostic technology that involves a patient gene expression signature that predicts severe sepsis, one of the significant diseases leading to antibiotic failure since antibiotics are the primary treatment for sepsis. Despite this, sepsis is responsible for nearly 20% of all deaths on the planet. The SepsetER test is a blood-based gene expression assay that is straightforward to implement, and results are obtained in about an hour in the emergency room or intensive care unit. This proprietary diagnostic technology differs from current diagnostic tests in enabling diagnosis of severe sepsis within 1-2 hours of first clinical presentation (i.e., in the emergency room), while other diagnostics only provide diagnosis after 24-36 hours. Asep Inc. believes this will enable critical early decisions to be made by physicians regarding appropriate therapies and reduce overall morbidity and mortality due to sepsis. FORWARD-LOOKING STATEMENTS This news release contains certain "forward-looking statements" within the meaning of such statements under applicable securities law. Forward-looking statements are frequently characterized by words such as "anticipates", "plan", "continue", "expect", "project", "intend", "believe", "anticipate", "estimate", "may", "will", "potential", "proposed", "positioned" and other similar words, or statements that certain events or conditions "may" or "will" occur. These statements include but are not limited to the completion of successful clinical testing of our Sepsis diagnostic test and its intended filing for regulatory approval; and the undertaking of pre-clinical studies on our lead therapeutic, with the expectation that this will lead to fast-track clinical trials. Various assumptions were used in drawing conclusions or making the predictions contained in the forward-looking statements throughout this news release. Forward-looking statements are based on the opinions and estimates of management at the date the statements are made and are subject to a variety of risks (including those risk factors identified in the Asep Medical Inc.'s prospectus dated November 9, 2021) available for review under the Company's profile at and uncertainties and other factors that could cause actual events or results to differ materially from those projected in the forward-looking statements. Asep Medical Inc. is under no obligation, and expressly disclaims any intention or obligation, to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, except as expressly required by applicable law. FOOTNOTES SOURCE ASEP Medical Holdings Inc.

Asia Pacific is Well Positioned as a Lucrative Dental Endodontics Market Backed by Favorable Oral Health Care Policies A recent assessment by Fact.MR provides detailed insights into factors affecting the pace of dental endodontics market growth. The report also offers incisive coverage on growth drivers and trends impacting the demand in terms of product and end-user across major regions. Fact.MR – A Market Research and Competitive Intelligence Provider: Globally the sales of dental endodontics are estimated to grow 2.3 times through 2021. As per Fact.MR, the global dental endodontics market is anticipated to exhibit 8.7% CAGR between 2021 and 2031. Consumers today are more aware about their oral care and dental hygiene. Negligence towards dental hygiene could lead to major oral disorders and health problems. Hence, adoption of dental endodontic consumables such as access cavity preparation and shaping & cleaning is increasing. High prevalence of oral problems such as dental decays, dental caries, and others, resulting in tooth cavities, has increased visits to dental clinics. However, people living in rural areas, especially across low income countries, have poor cases to dental clinics. This has compelled governments to focus on improving access to healthcare facilities and offer favorable reimbursement policies. This will continue supporting growth of the dental endodontics market. According to the World Health Organization (WHO), nearly 3.5 billion people are affected with oral diseases. More than 530 million children suffer from tooth decay, with countries across Asia Pacific, such as India, China, and Japan, recording the highest number of cases. Request a report sample to gain comprehensive insights at To contain this, governments in China and India are taking initiatives and collaborating with private organizations to spread the awareness about importance of maintaining proper dental hygiene. They also are adopting various strategies to make proper care better accessible. For instance, Government in India launched National Oral Health Program (NOHP) in 2020. This initiative included routine dental check-ups and encouraged Promotion of Public Private Partnerships (PPP) model for achieving better oral health. Through NOHP, states are provided necessary funds to establish dental care units, fortified with trained manpower, equipment including dental chair, and consumable dental materials. These initiatives have catapulted India and China as hotbeds for companies operating in the dental endodontics market. Besides this, integration of cutting-edge technologies such as 3D cone beam imaging technology is improving the adoption of dental endodontics instruments and consumables. “Due to the expanding patient pool across India, China, and Japan, key players are eyeing the Asia Pacific market to increase the sales of their advanced dental endodontics equipment and consumables. Also, favorable policies in these countries for dental care are expected to create growth opportunities for the market,” says the Fact.MR analyst. Key Takeaways from Dental Endodontics Market Study Dental clinics to remain key end user in dental endodontics market, holding over half the global sales In terms of product, dental consumables to account for largest market, with access cavity preparation leading the segment North America is expected to dominate the market with 30% of global revenue and the U.S. market leading the growth in the region India and China will lead the growth of Asia Pacific market, with the region contributing for over 45% of revenue Japan is likely to witness high demand at 6.3% CAGR owing to the increasing technological advancements in dental endodontics market Key Drivers Adoption of advanced technologies such as 3D cone beam imaging technology in dental procedures will reshape the growth in the market Increasing awareness regarding oral health and initiatives undertaken by government encouraging dental procedures for improved oral health will boost the market Key Restraints Lack of reimbursement plans for dental procedures in countries such as South Korea, India, and China might affect the sales negatively Ask Your Dental Endodontics Market Related Questions & Get Customized Reports Competitive Landscape Leading players are focusing on expanding their global reach through acquisitions of their rivals. Also, introduction of new product lines integrated with latest technology is the key strategy adopted by market players. For instance, In March 2021, BIOLASE Inc., global leader in dental lasers announced its collaboration with Einstein Healthcare Network residency in endodontics to train the endodontics residents in the use of Waterlase dental lasers. In December 2020, Sonoma Pharmaceuticals Inc., global leader developing oral, nasal, and other wide range products announced its partnership with Gabriel Science LLC for the sale of Microcyn® Technology products into the dental market and has accepted its first order. Endocyn®, a Microcyn® technology product manufactured by Sonoma, are biocompatible root canal irrigant that does not stain teeth or restorations. Dental Endodontics Market Players profiled by Fact.MR include: Dentsply Sirona Danaher Corporation Ivoclar Vivadent Mani, Inc. Ultradent Products, Inc. Peter Brasseler Holdings LP Septodont Holdings FKG Dentaire S.A. Mani Inc. Coltene Holding AG Henry Schein Inc. More Valuable Insights on Dental Endodontics Market Fact.MR, in its new report, offers comprehensive insights on the global dental endodontics market, analyzing forecast statistics through 2021 and beyond. The survey reveals growth projections on in the dental endodontics market with detailed segmentation: By Product: Dental Endodontic Instruments Endodontic Scalers & Lasers Motors Apex Locators Machine-assisted Obturation Systems Others Dental Endodontic Consumables Obturation Shaping and Cleaning Access Cavity Preparation By End User: Dental Hospitals Dental Clinics Dental Academic and Research Institutes Other Dental Endodontics End Users By Region: North America Latin America Europe East Asia South Asia Oceania Middle East & Africa Key Questions Covered in the Dental Endodontics Market Report The report offers insight into dental endodontics demand outlook for 2021-2031 The market survey also highlights projected sales growth for the dental endodontics market between 2021 and 2031 Dental endodontics market analysis identifies key growth drivers, restraints, and other forces impacting prevailing trends and evaluation of current market size and forecast and technological advancements within the industry Dental endodontics market share analysis of the key companies within the industry and coverage of strategies such as mergers & acquisitions, collaborations or partnerships, and others. Explore Fact.MR’s Coverage on the Healthcare Domain – Dental Restoratives Market- Over the last few years, the prevalence and severity of dental decay has decreased. Dental care requirements have resulted in a considerable shift in the type of dental care services, from traditional restorative to cosmetic and preventive. As a result of this shifting tendency, dental care providers have been compelled to produce technologically superior devices. Other generic factors, such as rising dental difficulties among the elderly, developing dental tourism, and an increase in the number of certified practitioners, are expected to boost the dental restoratives market. Dental Infection Control Products Market- In the dental infection control products market, digital dentistry is gaining a lot of traction, which will help the industry develop even faster. The global dental infection control products market is expanding rapidly, owing to increased demand for dental care products. This increase in demand is due to an increase in the incidence of oral diseases, a growing geriatric population with cavity issues, and changing lifestyles and eating habits. Furthermore, an increase in the number of skilled dentists is broadening access to oral care. As a result, the size of the market for dental infection control products is growing. Dental Consumables Market- The dental consumables market is expected to rise steadily, owing to increased cases of dental problems and rising demand for invasive dental operations. Increased dental tourism in developing nations like China and India, as well as an increasing senior population, are all contributing to this trend. Dental consumables are used to address a variety of dental conditions, including tooth restoration, gingival tissue problems, dental impairments, dental caries, and periodontal illnesses. The global expansion of the dental consumables market is being driven by an increase in the number of occurrences of dental issues. About Fact.MR Fact.MR is a market research and consulting agency with deep expertise in emerging market intelligence. Spanning a wide range – from automotive & industry 4.0 to healthcare, technology to even the most niche categories. 80% of Fortune 1000's trust us in critical decision making. MarketNgage is powered by Fact.MR – our Unified Intelligence Engine, a revolutionary Market Research Subscription platform with a flexible pricing to suit your needs. You can access all our healthcare research reports by signing up with MarketNgage’s Market Research Subscription with FREE credits. MarketNgage is powered by Fact.MR – A Fully integrated research solution for seamless single-window access Widest coverage on emerging markets, nascent products, and disruptive technologies. Contact: Mahendra Singh US Sales Office 11140 Rockville Pike Suite 400 Rockville, MD 20852 United States Tel: +1 (628) 251-1583 E: sales@factmr.com Source: Fact.MR

Consumable Denture Disinfectants to Command Over Half of Sales Registered by Top Players in Denture Disinfectants Market A Fact.MR market survey on the global dental disinfectants market provides a detailed overview of recent developments across various segments in the market including products and distribution channels. As per the report, sales of creams and pastes are poised to surge among various product categories. Fact.MR – A Market Research and Competitive Intelligence Provider: Rising awareness regarding oral health and denture care methodologies is spurring the demand for denture disinfectants. Denture cleaning units are largely preferred by customers as they are cost-effective, simpler, and easier to use. Considering this, Fact.MR has projected the global denture disinfectants market to expand at a steady rate over the assessment period. Denture stomatitis is one of the most common denture-related complications faced by patients who have been using dentures for a long period of time. Denture implant demand has increased in the last few recent years. This has resulted in higher focus on denture cleanliness and the removal of the microbial count, which is subsequently fuelling the demand for denture disinfectants. Besides this, rising prevalence of periodontal diseases among the geriatric population is asserting the need for advanced dental care and hygiene products. As per the World Health Organization (WHO), spending on dental treatment among people accounts for 5% of the total healthcare expenditure and 20% of out-of-pocket health expenditure. With rising disposable income across the globe, sales of denture disinfectants are anticipated to rise at a significant pace. Request a report sample to gain comprehensive insights at As per Fact.MR, North America will emerge as the most lucrative market for denture disinfectants, followed by Europe. Growth in these regions can be attributed to rising prevalence of edentulism. In addition to this, rapid adoption of modern healthcare solutions and methodologies, along with the presence of leading market players will continue augmenting growth of the denture disinfectants market in the forthcoming years. As per the report, Prestige Consumer Healthcare Inc and GlaxoSmithKline plc currently account for 49% of overall sales in the market. 50% of this is contributed by the sales of consumable denture disinfectants. “Launch of products such as portable ultrasonic denture cleaners, fresh breath strips, and denture rinse, along with easy availability and delivery of products through online retail channels will continue pushing sales of denture disinfectants through 2031," says the Fact.MR analyst. Key Takeaways from Denture Disinfectants Market Survey Sales of creams and pastes are anticipated to rise at a significant pace due to their cost-effectiveness, easy availability, and high effectiveness. Based on sales channel, retail sales will emerge as the most lucrative segment owing to easy access and availability of more product options. North America is projected to experience high demand for denture disinfectants due to growing geriatric population and the presence of key market players. Increasing incidence of edentulism in Europe will continue propelling sales of denture disinfectants. Cost-effective denture disinfectants launched by local players in China will place the country as an attractive market over the forecast period. Growth Drivers: Increasing demand denture implants due to age-related tooth loss will continue propelling sales of denture disinfectants. Introduction of biocompatible denture formats and modern disinfectants will boost sales of denture disinfectants over the forecast period. To learn more about Denture Disinfectants Market, you can get in touch with our Analyst at: Competitive Landscape Leading players operating in the global denture disinfectants market are investing in research and development activities to launch innovative products in the market. Apart from this, mergers, acquisitions, and strategic collaborations will remain prominent growth strategies among players over the forecast period. For instance, Colgate-Palmolive Company announced in January 2020 that it plans to acquire fastest growing oral care brand Hello Products LLC. Through this acquisition, Colgate-Palmolive Company aims at expanding its product portfolio. Key Producers of Denture Disinfectants Include: GlaxoSmithKline plc. Renfert GmbH ICPA Health Products Ltd Colgate-Palmolive Company Fittydent INTERNATIONAL GmbH Prestige Consumer Healthcare Inc. Procter & Gamble Johnson & Johnson Valplast International Corp. L&R Manufacturing Company More Valuable Insights on Denture Disinfectants Market Fact.MR provides an unbiased analysis of the denture disinfectants market, presenting historical demand data (2014-2018) and forecast statistics for the period from 2019-2029. The study divulges compelling insights on the global denture disinfectants market with a detailed segmentation on the basis of: Product: Ultrasonic Denture Cleaners Denture Cleaning Unit Consumables Tablets Creams and Pastes Gels and Solutions Distribution Channel: Institutional Sales Retail Sales Region: North America Latin America Europe South Asia East Asia Oceania Middle East & Africa Key Questions Covered in the Denture Disinfectants Market Report The report offers insight into denture disinfectants market demand outlook for 2019-2029 The market study also highlights projected sales growth for denture disinfectants market between 2019 and 2029 Denture disinfectants market survey identifies key growth drivers, restraints, and other forces impacting prevailing trends and evaluation of current market size and forecast and technological advancements within the industry Denture disinfectants market share analysis of the key companies within the industry and coverage of strategies such as mergers & acquisitions, joint ventures, collaborations or partnerships, and others Explore Fact.MR’s Coverage on the Healthcare Domain – Antiseptic and Disinfectant Market- The use of disinfectants and antiseptics has increased in a variety of situations, including healthcare, commercial, and residential. Since the outbreak of COVID-19, which highlighted the importance of maintaining personal and community hygiene, there has been a lot of buzz. Natural and organic disinfectants are becoming more popular among manufacturers. Manufacturers are developing various antiseptic and disinfectant products such as wipes, gels, disposable paper towels and alcohol-based solutions. Dental Infection Control Products Market- The global dental infection control products market is expanding rapidly, owing to increased demand for dental care products. This increase in demand is due to an increase in the incidence of oral diseases, a growing geriatric population with cavity issues, and changing lifestyles and eating habits. Furthermore, an increase in the number of skilled dentists is broadening access to oral health care. As a result, the size of the market for dental infection control products is growing. Prophylaxis Pastes Market- The market has grown as the prevalence of dental problems such as periodontal disease has increased due to poor oral hygiene. As people become more aware of the need of dental care, the market for prophylaxis pastes is expected to develop. Companies, on the other hand, are working on introducing a dental solution that would provide the benefits of dental hygiene, hence driving market growth. Due to an increasing awareness of health and dental safety as a result of changing lifestyles, Europe leads the market for prophylaxis pastes. About Fact.MR Market research and consulting agency with a difference! That’s why 80% of Fortune 1,000 companies trust us for making their most critical decisions. We have offices in US and Dublin, whereas our global headquarter is in Dubai. While our experienced consultants employ the latest technologies to extract hard-to-find insights, we believe our USP is the trust clients have on our expertise. Spanning a wide range – from automotive & industry 4.0 to healthcare & retail, our coverage is expansive, but we ensure even the most niche categories are analyzed. Reach out to us with your goals, and we’ll be an able research partner. Contact: Mahendra Singh US Sales Office 11140 Rockville Pike Suite 400 Rockville, MD 20852 United States Tel: +1 (628) 251-1583 E: sales@factmr.com Source: Fact.MR