Synonyms ARTERIOSCLEROSIS OBLITERANS, Arteriosclerosis Obliterans, Arteriosclerosis obliterans + [11] |
Introduction Common occlusive arterial disease which is caused by ATHEROSCLEROSIS. It is characterized by lesions in the innermost layer (ARTERIAL INTIMA) of arteries including the AORTA and its branches to the extremities. Risk factors include smoking, HYPERLIPIDEMIA, and HYPERTENSION. |
Target |
Mechanism c-Met modulators |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. JP |
First Approval Date26 Mar 2019 |
Target |
Mechanism PGI2 receptor agonists |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. US |
First Approval Date21 Dec 2015 |
Target |
Mechanism thrombin inhibitors |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. JP |
First Approval Date16 Apr 1996 |
Start Date01 Jan 2024 |
Sponsor / Collaborator- |
Start Date01 Jan 2024 |
Sponsor / Collaborator |
Start Date01 Nov 2023 |
Sponsor / Collaborator- |