Acne Keloid

LOS ANGELES, Sept. 5, 2023 /PRNewswire/ -- Researchers at Dr. U Hair and Skin Clinic in Los Angeles uncover a crucial link between two medically challenging conditions - Acne Keloidalis Nuchae and Primary Cicatricial Alopecias often called scarring alopecias. Published in the Clinical Cosmetic and Investigational Dermatology journal under "Unveiling a Common Precursor Condition for Acne Keloidalis Nuchae and Primary Cicatricial Alopecias," the findings have significant implications for diagnostics and treatments. Continue Reading PIILIF is a root condition that potentially links all common scarring alopecias Tweet this Researchers link all common scarring alopecias to a single root condition called PIILIF (perifollicular infundibulo-isthmic lymphocytic infiltrates and fibrosis) Acne Keloidalis Nuchae (AKN) is one of a group of scalp conditions called scarring alopecias, known for chronic inflammation causing scarring hair loss with pain, discharge, itching, and social debilitation. AKN often results in disfiguring keloid-like lesions. The research investigated hidden links and shared root conditions. Traditionally, AKN and scarring alopecias were studied in isolation. This research reveals a link called "Perifollicular Infundibulo-Isthmic Lymphocytic Infiltrates Fibrosis" (PIILIF), identified in the normal-appearing scalp (NAS) zones of all AKN patients. PIILIF could shed light on early AKN and scarring alopecia stages. Dr. Sanusi Umar, the study's lead researcher, also head of the scalp and hair disorder section at Harbor-UCLA's dermatology division, underscores that this discovery suggests the potential for more precise therapies targeting root causes and refining diagnostic strategies. Dr. Umar explained, "Our findings, along with other studies, suggest that PIILIF potentially links all common scarring alopecias, such as AKN, folliculitis decalvas (FD), lichen planopilaris (LPP), frontal fibrosing alopecia, and central centrifugal cicatricial alopecia. This highlights their interconnections, offering new insights into their origins and enabling a more holistic diagnostic and therapeutic strategy. Moreover, this might streamline the intricate classification of scarring alopecias by reducing redundancies in closely related conditions. For instance, our research questions the necessity of the entity currently designated LPP-FD phenotype." Surprisingly, the study found AKN to be more prevalent than previously realized in European-descended White males (10% of patients), often unnoticed or misdiagnosed as nape irritation or dandruff. This finding challenges AKN's perception as solely affecting people of color. The study has significant implications, potentially reshaping our understanding of AKN, scarring alopecia, and treatments. Further research is needed to uncover PIILIF's mechanisms, triggers, and role in hair loss. Nonetheless, this work paves the way for improved diagnosis, treatment, and patient well-being. For media inquiries, please contact: Sara Harutyunyan Dr. U Hair and Skin Clinic sara@dru.com SOURCE Dr. U Hair and Skin Clinic

LOS ANGELES, Aug. 28, 2023 /PRNewswire/ -- Dr. U Hair and Skin Clinic announces a recent research report has illuminated a potential breakthrough in treating Acne Keloidalis Nuchae (AKN), a chronic and burdensome condition. The study titled "Papular Acne Keloidalis Nuchae Treatment Success using Follicular Unit Excision" was published in the Journal of The American Academy of Dermatology – JAAD Case Reports. Continue Reading Our study suggests that FUE could be a promising treatment for AKN, particularly when hair-bearing papules are involved. Tweet this Three acne keloidalis nuchae (AKN) patients were successfully treated by FUE using UGraft Zeus AKN is marked by persistent inflammation, scarring hair loss (Alopecia), and distressing symptoms, including malodorous discharge, keloid-like lesions, discomfort, itching, and social difficulties. While it predominantly impacts men of color, recent studies have shown that European-descended Whites account for 9-10% of cases, with women affected the least. The study reports the first-time use of a procedure called Follicular Unit Excision (FUE), often used in hair transplantation, as a potential remedy for AKN. FUE targets individual hair follicles within visible AKN papules, aiming to halt the disease while minimizing scarring. The research highlights positive outcomes in three patients who underwent this FUE-based approach. Dr. Sanusi Umar, the lead author of the study and associated with the University of California Los Angeles, Harbor-UCLA, Torrance, and Dr. U Hair and Skin Clinic, Manhattan Beach, explains, "Our study suggests that FUE could be a promising treatment for AKN, particularly when hair-bearing papules are involved. This method holds the potential for lasting remission while preserving the patient's appearance." The study delves into the methods used, patient selection criteria, and the innovative FUE technology UGraft Zeus® (Dr. U Devices Inc., Manhattan Beach, CA), which enables the extraction of AKN-affected often-curly hair deeply embedded in scar tissue. The research emphasizes the importance of specialized FUE devices and minimizing the risk of damage to hair follicles. Patients with confirmed AKN lesions who had not responded to standard treatments experienced lasting relief after a single FUE-based treatment session. The research advances our understanding of AKN and opens a potential avenue for effective treatment. These findings offer hope to individuals dealing with AKN and healthcare professionals seeking novel strategies to address the condition. For inquiries and interviews, please contact: Sara Harutyunyan Dr. U Devices Inc sara@dru.com SOURCE Dr. U Hair and Skin Clinic