Last update 23 Jan 2025

Accelerated phase Philadelphia chromosome positive chronic myeloid leukemia

Basic Info

Synonyms-
Introduction-

Related

2
Drugs associated with Accelerated phase Philadelphia chromosome positive chronic myeloid leukemia
Nilotinib Hydrochloride
Target
Bcr-Abl x CSF-1R x DDR1 x PDGFR x c-Kit
Mechanism
Bcr-Abl inhibitors [+4]
Active Org.
Novartis Pharmaceuticals Corp.Novartis Pharmaceuticals Corp. [+10]
Originator Org.
Novartis Pharma AG
Active Indication
Aggressive-Phase Chronic Myelocytic Leukemia [+9]
Inactive Indication
Acoustic Neuroma [+27]
Drug Highest PhaseApproved
First Approval Ctry. / Loc.
CH
First Approval Date24 Jul 2007
Imatinib mesylate
Target
ABL x Bcr-Abl x PDGFR x c-Kit
Mechanism
ABL inhibitors [+3]
Active Org.
National Cancer InstituteNational Cancer Institute [+11]
Originator Org.
Novartis Pharma AG
Active Indication
Accelerated phase Philadelphia chromosome positive chronic myeloid leukemia [+33]
Inactive Indication
Abdominal Neoplasms [+171]
Drug Highest PhaseApproved
First Approval Ctry. / Loc.
US
First Approval Date10 May 2001
1
Clinical Trials associated with Accelerated phase Philadelphia chromosome positive chronic myeloid leukemia
NCT03414450
/ WithdrawnPhase 1IIT
A Phase 1A Dose Escalation and Phase 1B Expansion Study to Evaluate the Safety and Tolerability of ETC-1907206 in Combination With Dasatinib in Advanced Haematologic Malignancies
100 Clinical Results associated with Accelerated phase Philadelphia chromosome positive chronic myeloid leukemia
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100 Translational Medicine associated with Accelerated phase Philadelphia chromosome positive chronic myeloid leukemia
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0 Patents (Medical) associated with Accelerated phase Philadelphia chromosome positive chronic myeloid leukemia
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