Last update 07 Nov 2024

Amoxicillin/Omeprazole Magnesium/Rifabutin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Amoxicillin/Omeprazole/Rifabutin, Amoxicillin/pantoprazole/rifabutin, Amoxicillin/rifabutin/omeprazole
+ [6]
Mechanism
50S subunit inhibitors(50S ribosomal subunit inhibitors), Proton pump inhibitors, RNA polymerase II inhibitors
Therapeutic Areas
Inactive Indication
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
RegulationQualified Infectious Disease Product (US), Fast Track (US)
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Structure

Molecular FormulaC16H21N3O6S
InChIKeyAIPFZZHNBUVELL-YWUHCJSESA-N
CAS Registry61336-70-7
View All Structures (3)

External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Helicobacter pylori infection
US
01 Nov 2019
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
DyspepsiaPhase 3
US
01 Nov 2013
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
293
(patients with DM)
mkusyzfbab(domchtmlcv) = bkporxqemd ioyzxgpapv (nehbynqevn )
Positive
25 May 2022
(patients without DM)
mkusyzfbab(domchtmlcv) = fbpbtlsgya ioyzxgpapv (nehbynqevn )
Phase 3
455
hgbhfilxtw(evlziyxaup) = The most commonly reported adverse events (incidence ≥5%) were diarrhea (10.1% with RHB-105 vs. 7.9% with active comparator), headache (7.5% vs. 7.0%), and nausea (4.8% vs. 5.3%). mruxpemext (mmltqcferq )
Superior
16 Jun 2020
amoxicillin+omeprazole
Phase 3
455
(RHB-105)
jyyxnwgumv(otbibvsfgm) = ffcckjzhzq arxwtrwpvg (pujxhvcytf, slfynxeqwp - nuxubcejjz)
-
16 Mar 2020
Active Comparator
(Active Comparator)
jyyxnwgumv(otbibvsfgm) = sthxxqhtrd arxwtrwpvg (pujxhvcytf, tsbsaupiim - nfnsbduiqi)
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Approval

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Regulation

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