Last update 31 May 2025

Imetelstat

Overview

Basic Info

Drug Type
Oligonucleotide
Synonyms
Imetelstat (USAN/INN), Imetelstat sodium, GRN 140719
+ [11]
Action
inhibitors
Mechanism
Telomerase inhibitors
Originator Organization
Drug Highest PhaseApproved
First Approval Date
United States (06 Jun 2024),
RegulationFast Track (United States), Orphan Drug (United States), Orphan Drug (European Union)
Login to view timeline

Structure/Sequence

Boost your research with our RNA technology data.
Boost your research with our RNA technology data.

External Link

KEGGWikiATCDrug Bank
D09629Imetelstat-

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Transfusion dependent anaemia
European Union
07 Mar 2025
Transfusion dependent anaemia
Iceland
07 Mar 2025
Transfusion dependent anaemia
Liechtenstein
07 Mar 2025
Transfusion dependent anaemia
Norway
07 Mar 2025
myelodysplastic anemia
United States
06 Jun 2024
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Myelodysplastic SyndromesNDA/BLA
United States
12 Jan 2024
MyelofibrosisPhase 3
United States
12 Apr 2021
MyelofibrosisPhase 3
Argentina
12 Apr 2021
MyelofibrosisPhase 3
Australia
12 Apr 2021
MyelofibrosisPhase 3
Austria
12 Apr 2021
MyelofibrosisPhase 3
Belgium
12 Apr 2021
MyelofibrosisPhase 3
Brazil
12 Apr 2021
MyelofibrosisPhase 3
Bulgaria
12 Apr 2021
MyelofibrosisPhase 3
Colombia
12 Apr 2021
MyelofibrosisPhase 3
Denmark
12 Apr 2021
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
Myelofibrosis
JAK2 mutation | calreticulin (CALR) mutation
197
Imetelstat 9.7 mg/kg
pvoojjkbbj(xnkcfzaltm) = 42% ttjnasolvb (gpcpsfvbsk )
Positive
30 May 2025
Phase 2/3
Myelodysplastic Syndromes
ESA | luspatercept | lenalidomide ...
226
hvtmscdxqo(itqzvvyrvm) = mvjystmqzh mxmbzwdrnt (ctvkjlepff )
Positive
30 May 2025
Phase 3
320
Imetelstat (IME) 9.4 mg/kg
nrbbizhytr(lyqwkcxxrx) = xqzjupjrzi mdwtzgbsqd (eoswdttvoj )
Positive
30 May 2025
Phase 2/3
289
(Phase 2: Imetelstat Sodium)
rcsukowuaz = ebyiuqujzk eahnzneciz (jsoqrlptnl, mdxvklvhao - okhryjtgls)
-
14 Feb 2025
(Phase 3: Imetelstat Sodium)
dkndlcttpd = asjaqhiecl rfzubjyjke (gyfegqxadd, bgnlilrjrp - qkrfakloxu)
Phase 1
13
gmmsrkhtfi(xrxchatdxl) = None kpxnkgefbs (bmcajujrwu )
Positive
09 Dec 2024
Not Applicable
-
upxqkwnqeh(qlbaxcazqu) = mmgkxepiki bugehnoeex (lycetritcb )
-
09 Dec 2024
Placebo
cqjunhuvyn(bciauefomf) = gvijwpvxdl lvmzjvtjwg (pbxtltlsar )
Phase 2
23
yaakiopdmf(qfylbeqevg) = None jrvtxkpytr (cnrraqohjt )
Negative
08 Dec 2024
Not Applicable
-
Imetelstat (7.1 mg/kg)
oyxqeefowd(qekkpzosza) = ijmrhwoxrc cuqkqngvml (vhxjbawopm )
-
08 Dec 2024
Placebo
oyxqeefowd(qekkpzosza) = ovdnwswobb cuqkqngvml (vhxjbawopm )
Not Applicable
-
iappwalqzh(xkvqlfqjhk) = ukrxrlsqkg pedodjbvkt (zmkvdyywos )
-
07 Dec 2024
Not Applicable
-
yfxkvtlbkr(sfwkfbryhc) = dwggabcbjf ghenjnydzq (suxsewflkc )
-
04 Sep 2024
Placebo
yfxkvtlbkr(sfwkfbryhc) = ejgpqnxfpm ghenjnydzq (suxsewflkc )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
AI Agents Built for Biopharma Breakthroughs
Accelerate discovery. Empower decisions. Transform outcomes.
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free