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Clinical Trials associated with Chlorobenzopiperidone Hydrochloride盐酸氯苯哌酮片对 (全或半)髋/膝关节置换术后镇痛效果的探索及群体药代动力学研究
[Translation] Exploration of the analgesic effect of clopidogrel hydrochloride tablets on postoperative analgesia after (total or partial) hip/knee replacement and population pharmacokinetic study
本试验作为治疗作用初步评价阶段: 1、观察盐酸氯苯哌酮片300mg剂量组镇痛效果及维持时间; 2、进行人体PK/PD试验,探讨原药及其代谢产物的暴露量与疗效的关系; 3、观察药物的安全性; 为下一步临床试验研究设计提供安全性和有效性依据。
[Translation] This trial serves as the preliminary evaluation stage of the therapeutic effect: 1. To observe the analgesic effect and maintenance time of the 300 mg dose group of chlorpheniramine hydrochloride tablets; 2. To conduct human PK/PD tests to explore the relationship between the exposure amount of the original drug and its metabolites and the therapeutic effect; 3. To observe the safety of the drug; To provide a safety and effectiveness basis for the next step of clinical trial research design.
不同剂量盐酸氯苯哌酮片对髋膝关节置换术后镇痛效果的探索性临床试验
[Translation] An exploratory clinical trial of different doses of clopidogrel hydrochloride tablets for analgesia after hip and knee replacement surgery
本试验作为治疗作用初步评价阶段: 1、观察不同剂量镇痛效果及维持时间,找出最佳的治疗剂量; 2、进行人体PK/PD试验,探讨原药及其代谢产物的暴露量与疗效的关系; 3、观察药物的安全性; 为下一步的临床试验研究提供设计和给药剂量的依据。
[Translation] This trial serves as a preliminary evaluation stage for therapeutic effects: 1. Observe the analgesic effect and maintenance time of different doses to find the optimal therapeutic dose; 2. Conduct human PK/PD tests to explore the relationship between the exposure of the original drug and its metabolites and the therapeutic effect; 3. Observe the safety of the drug; Provide a basis for the design and dosage of the next clinical trial research.
100 Clinical Results associated with Chlorobenzopiperidone Hydrochloride
100 Translational Medicine associated with Chlorobenzopiperidone Hydrochloride
100 Patents (Medical) associated with Chlorobenzopiperidone Hydrochloride
100 Deals associated with Chlorobenzopiperidone Hydrochloride