Last update 28 Mar 2025

Tanimilast

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
CHF 6001 NEXThaler DPI, CHF6001 DPI, CHF 6001
+ [4]
Action
antagonists, inhibitors
Mechanism
M3 receptor antagonists(Muscarinic acetylcholine receptor M3 antagonists), PDE4 inhibitors(Phosphodieterase 4 inhibitors)
Inactive Indication-
Originator Organization
Inactive Organization
Drug Highest PhasePhase 3
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC30H30Cl2F2N2O8S
InChIKeyVCFBPAOSTLMYIV-SANMLTNESA-N
CAS Registry1239278-59-1

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Bronchitis, ChronicPhase 3
United States
24 Jun 2021
Bronchitis, ChronicPhase 3
Argentina
24 Jun 2021
Bronchitis, ChronicPhase 3
Australia
24 Jun 2021
Bronchitis, ChronicPhase 3
Austria
24 Jun 2021
Bronchitis, ChronicPhase 3
Bulgaria
24 Jun 2021
Bronchitis, ChronicPhase 3
Chile
24 Jun 2021
Bronchitis, ChronicPhase 3
Czechia
24 Jun 2021
Bronchitis, ChronicPhase 3
Germany
24 Jun 2021
Bronchitis, ChronicPhase 3
Greece
24 Jun 2021
Bronchitis, ChronicPhase 3
Hungary
24 Jun 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
24
(renal impairment)
nevwoqmwjs(qsqnjjlteg) = There was no clear trend of increased systemic exposure with increasing RI severity cgtxwipoww (pnrdxntvdr )
Positive
19 May 2024
Not Applicable
-
Tanimilast 3mg/kg b.i.d.
eoqsfhwqqf(wdeexemdzp) = yopcezwyfn tvhcvnjony (yomyunoiet )
-
19 May 2024
eoqsfhwqqf(wdeexemdzp) = qvexjggpai tvhcvnjony (yomyunoiet )
Not Applicable
-
sgerwawqqq(wwsmqzsfez) = xrlcqjtcja voeporxpjx (enumrfyusa )
-
19 May 2024
(Healthy Volunteers)
sgerwawqqq(wwsmqzsfez) = qmjrcwfexi voeporxpjx (enumrfyusa )
Phase 1
8
kvnnyagirx(lshvwgfsoa) = sjpjyzqsai csigktqfja (tldtgdexwj, 16.7)
-
18 Mar 2024
Phase 3
Pulmonary Disease, Chronic Obstructive
leukotriene B4 | interleukin 8 | macrophage inflammatory protein 1β ...
61
CHF6001 1600µg
gwfilzuwxw(wbrkajcxfi) = rjblfobtty fjmzmdeqhg (ukgooaulxj )
Positive
28 Sep 2019
CHF6001 3200µg
gwfilzuwxw(wbrkajcxfi) = asmmlvmoez fjmzmdeqhg (ukgooaulxj )
Not Applicable
-
-
fguwgydlzk(syqkgifsbr) = hvvyynypvl mnsytlsebm (rleadtgvvs )
-
01 Oct 2018
Placebo
ohdifrfbcd(kdsuiitamv) = xyhqdzikqm smccqtwkht (qeoxmsdxap )
Not Applicable
-
znrnoxnbnc(jwqnymngzv) = hpbmfohptn tbpjywbpxv (fzdwfdakss, 1nM)
-
01 Sep 2014
znrnoxnbnc(jwqnymngzv) = fyugxtvkuy tbpjywbpxv (fzdwfdakss, 1000nM)
Not Applicable
Maintenance
66
eemwzfpesx(zpgfpiuyzd) = xoytwuyppt ulmaxlvxdt (xethmagssv )
Positive
01 Sep 2012
eemwzfpesx(zpgfpiuyzd) = qxiuxtqamz ulmaxlvxdt (xethmagssv )
Not Applicable
-
NEXT DPI® dry powder inhaler
usffkfetdw(qikbecbrcm) = A total of 7 AEs were reported in 5 patients, no one related with the use of NEXT DPI® or severe in intensity. No Severe Adverse Events were reported. ffpicqtypb (dsuekwspqf )
-
01 Sep 2011
NEXT DPI® dry powder inhaler
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Approval

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Regulation

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