Last update 01 Nov 2024

Tanimilast

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
CHF 6001 NEXThaler DPI, CHF6001 DPI
+ [4]
Mechanism
M3 receptor antagonists(Muscarinic acetylcholine receptor M3 antagonists), PDE4 inhibitors(Phosphodieterase 4 inhibitors)
Inactive Indication-
Originator Organization
Inactive Organization
Drug Highest PhasePhase 3
First Approval Date-
Regulation-
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Structure

Molecular FormulaC30H30Cl2F2N2O8S
InChIKeyVCFBPAOSTLMYIV-SANMLTNESA-N
CAS Registry1239278-59-1

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Bronchitis, ChronicPhase 3
GR
24 Jun 2021
Bronchitis, ChronicPhase 3
ES
24 Jun 2021
Bronchitis, ChronicPhase 3
ZA
24 Jun 2021
Bronchitis, ChronicPhase 3
NL
24 Jun 2021
Bronchitis, ChronicPhase 3
MX
24 Jun 2021
Bronchitis, ChronicPhase 3
PL
24 Jun 2021
Bronchitis, ChronicPhase 3
RO
24 Jun 2021
Bronchitis, ChronicPhase 3
UA
24 Jun 2021
Bronchitis, ChronicPhase 3
GB
24 Jun 2021
Bronchitis, ChronicPhase 3
IT
24 Jun 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
24
(renal impairment)
(ufjksjqnxq) = There was no clear trend of increased systemic exposure with increasing RI severity jasmuvarue (slyzuhgtte )
Positive
19 May 2024
Phase 1
8
xhbmswhijh(ijthdotlih) = afifipsexq nxnqycrcze (kcnkqqsyvo, zwbxehfeiy - vvvwzsbrxl)
-
18 Mar 2024
Not Applicable
-
-
(kkleozdpxj) = larclpoocw ghfihjwevc (fcxvnkciyt )
-
01 Oct 2018
Placebo
xvzmnhujps(myiklsdqnk) = khgcclhixl mifmpnvtbk (sxcoftsxga )
Not Applicable
-
oixkurftyk(fvpnyzbsiz) = buezmznnhp qhdyicgqwc (zyxwwyedag, 1nM)
-
01 Sep 2014
oixkurftyk(fvpnyzbsiz) = wyutoqwltg qhdyicgqwc (zyxwwyedag, 1000nM)
Not Applicable
Maintenance
66
ievsaqfhwp(pbbgewbphh) = rxbuzixocw pljmseepmu (reboemftad )
Positive
01 Sep 2012
ievsaqfhwp(pbbgewbphh) = ysqzoruhpt pljmseepmu (reboemftad )
Not Applicable
-
NEXT DPI® dry powder inhaler
etueldqypc(dpojkelwts) = A total of 7 AEs were reported in 5 patients, no one related with the use of NEXT DPI® or severe in intensity. No Severe Adverse Events were reported. masyjmyolc (mnxdsxcfgs )
-
01 Sep 2011
NEXT DPI® dry powder inhaler
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Regulation

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