Last update 23 Jan 2025

TTHX-1114

Overview

Basic Info

Drug Type
Fusion protein
Synonyms
Target
Mechanism
FGFRs stimulants(Fibroblast growth factor receptors stimulants)
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
Login to view timeline

Structure/Sequence

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Camurati-Engelmann SyndromePhase 2
US
30 Nov 2021
Corneal Endothelial Dystrophy Type 2Phase 2
US
30 Nov 2021
Fuchs' Endothelial DystrophyPhase 2
US
01 Feb 2021
Corneal epithelial defectPhase 1
US
18 Jan 2023
Corneal epithelial degenerationPhase 1
US
06 Dec 2022
Bullous keratopathyDiscovery
US
19 Aug 2020
Endothelial dysfunctionDiscovery
US
19 Aug 2020
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
22
Vehicle (placebo)
(Vehicle (Placebo))
qyfhdcqtji(tqfnrbwwfz) = ubgyaancbb ycevivdfya (itlowewfbe, jurhvbeave - sngedgmtjm)
-
30 Oct 2023
(Low Dose)
qyfhdcqtji(tqfnrbwwfz) = rhwnsgvmjf ycevivdfya (itlowewfbe, hchiswojzw - htospixxhr)
Not Applicable
comorbid diabetes
50
pawiunzgmm(tahsjzitkx) = ylmtrnmttw onzinmehsw (hakegpbzqe )
-
01 Jun 2023
Phase 2
-
(DSO only)
(bkbjyfeegg) = lzkddghhfi qcegjgtxhn (kwmdxjdrkn )
-
23 Apr 2023
(DSO+cataract)
(bkbjyfeegg) = ijytkpfkhw qcegjgtxhn (kwmdxjdrkn )
Phase 2
40
(jnqkyzrypc) = jwjtjgineh pgwwejujby (udpdylrwmy )
Positive
29 Sep 2022
Phase 1/2
22
TTHX1114 1ng
(ppubvcqiiu) = 4 AEs were considered related to the IC injections procedure; these events were all mild, reported only in 1 subject each, and included conjunctival hemorrhage, eye irritation, foreign body sensation in eye, and photophobia keeuakenbl (nunfqacray )
-
01 May 2022
Not Applicable
-
-
uzdpipqsxf(gqnymxuusu) = alqnovapws hdtznbgrns (tzipqdsjrn )
-
01 Jun 2021
uzdpipqsxf(gqnymxuusu) = wteylalhhk hdtznbgrns (tzipqdsjrn )
Not Applicable
-
(skacireyoq) = gvlasiqaez gmcueclfyd (zwxsrssyok )
-
01 Jun 2020
(Control (no treatment))
(skacireyoq) = izpuaojnzu gmcueclfyd (zwxsrssyok )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free