Last update 07 Nov 2024

Methyldopa

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(S)-(-)-alpha-Methyldopa, 3-Hydroxy-alpha-methyl-L-tyrosine, Alpha medopa
+ [23]
Target
Mechanism
ADRA2 agonists(Adrenergic receptors alpha-2 agonists)
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (20 Dec 1962),
RegulationOrphan Drug (US), Fast Track (US)
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Structure

Molecular FormulaC20H32N2O11
InChIKeyYKFCISHFRZHKHY-NGQGLHOPSA-N
CAS Registry41372-08-1

External Link

KEGGWikiATCDrug Bank
D00405Methyldopa

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hypertension
US
20 Dec 1962
Hypertension
US
20 Dec 1962
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Retinopathy of PrematurityPhase 2
US
-
Diabetes Mellitus, Type 1Phase 1
US
09 Nov 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
54
ACE inhibitors
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Positive
28 Aug 2020
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Not Applicable
30
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-
29 Mar 2018
Not Applicable
419
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-
01 Mar 2012
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Approval

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Regulation

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