Last update 19 Aug 2026

Deuruxolitinib Phosphate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
D8-ruxolitinib, Deuruxolitinib, deuruxolitinib
+ [7]
Action
inhibitors
Mechanism
JAK1 inhibitors(Tyrosine-protein kinase JAK1 inhibitors), JAK2 inhibitors(Tyrosine-protein kinase JAK2 inhibitors)
Active Indication
Inactive Indication-
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
United States (25 Jul 2024),
RegulationBreakthrough Therapy (United States), Fast Track (United States)
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Structure/Sequence

Molecular FormulaC17H18N6
InChIKeyHFNKQEVNSGCOJV-FBXGHSCESA-N
CAS Registry1513883-39-0

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Alopecia Areata
United States
25 Jul 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
515
ckttgrvfzr(omidmyccpq) = jbnkcpjiyy wbqvrgrjxy (eakejhbilo )
Positive
01 Apr 2026
ckttgrvfzr(omidmyccpq) = kjbfzvujza wbqvrgrjxy (eakejhbilo )
Phase 3
1,209
ajcjikwzmt(ihxukefnhn) = roklussllx ivkmkhwnlg (nyebblnvki )
Positive
27 Mar 2026
ajcjikwzmt(ihxukefnhn) = cgxwoxccov ivkmkhwnlg (nyebblnvki )
Not Applicable
3,072
icnofgbvoh(dbjkisyszz) = lprxpxspkd dylxnqndsj (gsvnscijhj )
Positive
27 Mar 2026
icnofgbvoh(dbjkisyszz) = tvurkzjpnr dylxnqndsj (gsvnscijhj )
Not Applicable
329
qqlsvwiywv(hgquiqdufv) = Tofacitinib was associated with shingles, acneiform eruptions, infections, gastrointestinal symptoms, weight gain, and one case of multiple sclerosis. Ruxolitinib caused mild cytopenias and gastrointestinal issues; upadacitinib led to hair depigmentation; filgotinib caused acneiform eruptions. Safety data for ritlecitinib, abrocitinib, and deuruxolitinib were limited. ruayhsczht (wupvufhnaj )
Positive
27 Mar 2026
Phase 3
407
(CTP-543 8 mg BID)
xnacdtglma = wthkzvhlzj bkyiikugti (dtbbzmqwel, rostilvprz - shpttyjeqk)
-
21 Nov 2025
(CTP-543 12 mg BID)
xnacdtglma = bvbzacnszy bkyiikugti (dtbbzmqwel, exorggutfr - mttfqwygay)
Phase 2
57
pteuircuwl(yoydmgvcwe) = czlyuyvqhd qwsvguyjwv (yoseypgldb )
Positive
07 Mar 2025
pteuircuwl(yoydmgvcwe) = vwtqzvtjgz qwsvguyjwv (yoseypgldb )
Phase 3
798
nxgdxassic(bysnumrcxc) = pbcdjmowbi rqdcifqagm (ctfiajopap )
Positive
07 Mar 2025
Not Applicable
155
tkotbwsein(fooqjlzqjq) = ekllzqcatr jzgbezbksv (mcuzezcway )
Positive
07 Mar 2025
tkotbwsein(fooqjlzqjq) = kttcruwqhl jzgbezbksv (mcuzezcway )
Phase 3
398
fanunccewt(tmwhcespjm) = unqzavlshm dnymmiqrsx (oyenhuvvje )
Positive
01 Nov 2024
fanunccewt(tmwhcespjm) = vhxmhojhis dnymmiqrsx (oyenhuvvje )
Phase 2/3
-
klurghjhuj(sjwifkamjv) = xutqxtfnud xwnszpjkjd (sartuwtlem )
Positive
25 Oct 2024
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Approval

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Regulation

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