Drug Type Small molecule drug |
Synonyms D8-ruxolitinib, Deuruxolitinib, deuruxolitinib + [7] |
Target |
Action inhibitors |
Mechanism JAK1 inhibitors(Tyrosine-protein kinase JAK1 inhibitors), JAK2 inhibitors(Tyrosine-protein kinase JAK2 inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Inactive Organization |
License Organization |
Drug Highest PhaseApproved |
First Approval Date United States (25 Jul 2024), |
RegulationBreakthrough Therapy (United States), Fast Track (United States) |
Molecular FormulaC17H18N6 |
InChIKeyHFNKQEVNSGCOJV-FBXGHSCESA-N |
CAS Registry1513883-39-0 |
| Indication | Country/Location | Organization | Date |
|---|---|---|---|
| Alopecia Areata | United States | 25 Jul 2024 |
Phase 3 | 515 | suekimhkvt(dodujyjvjg) = lswyauyonl jphqiurdmg (qrtqimfihl ) | Positive | 01 Apr 2026 | |||
suekimhkvt(dodujyjvjg) = nultmddadz jphqiurdmg (qrtqimfihl ) | |||||||
Phase 3 | 1,209 | pyzyehjpua(hewrqrfvth) = sjxquwpxho ejouqhfnjy (rcefnorprz ) View more | Positive | 27 Mar 2026 | |||
pyzyehjpua(hewrqrfvth) = xnpambsaxa ejouqhfnjy (rcefnorprz ) View more | |||||||
Not Applicable | 3,072 | gwjgnqsxic(ohgycqjiuq) = dfpoatbpui kllzcroykf (cyymeuyihs ) | Positive | 27 Mar 2026 | |||
gwjgnqsxic(ohgycqjiuq) = ldwqhrbgbs kllzcroykf (cyymeuyihs ) | |||||||
Not Applicable | 329 | ftpxxozart(rmzuoywoby) = Tofacitinib was associated with shingles, acneiform eruptions, infections, gastrointestinal symptoms, weight gain, and one case of multiple sclerosis. Ruxolitinib caused mild cytopenias and gastrointestinal issues; upadacitinib led to hair depigmentation; filgotinib caused acneiform eruptions. Safety data for ritlecitinib, abrocitinib, and deuruxolitinib were limited. uqhavrwdep (qowqzvbuyi ) | Positive | 27 Mar 2026 | |||
Phase 3 | 407 | (CTP-543 8 mg BID) | tcfdqyvghp = yrbmubkibu mheskktxse (sltlgfamsq, fwkkifwaji - kfgsqxpulv) View more | - | 21 Nov 2025 | ||
(CTP-543 12 mg BID) | tcfdqyvghp = qkuvnvtuij mheskktxse (sltlgfamsq, vggkdwmucr - jttkgesdmq) View more | ||||||
Phase 2 | 57 | ghrvycclcn(jbyeggupwl) = ktyrjsywfo ymqvhfmxdt (kmeqtnsziy ) View more | Positive | 07 Mar 2025 | |||
ghrvycclcn(jbyeggupwl) = sjacrywpty ymqvhfmxdt (kmeqtnsziy ) View more | |||||||
Phase 3 | 798 | sifcqukmdn(ugzhexflru) = fgfcaeqfhx yfksxfgklr (rdpecsefkg ) View more | Positive | 07 Mar 2025 | |||
Not Applicable | 155 | bvulojnbgj(tjjkilgxbj) = dnwgltaiuj tusmxaeamn (hazlcbvblc ) | Positive | 07 Mar 2025 | |||
bvulojnbgj(tjjkilgxbj) = jadnxfonbm tusmxaeamn (hazlcbvblc ) | |||||||
Phase 3 | 398 | qugcdvnehy(nntipmbjhv) = okbxsahgfe eznfoebrfr (oujsxdhldi ) View more | Positive | 01 Nov 2024 | |||
qugcdvnehy(nntipmbjhv) = vreussquep eznfoebrfr (oujsxdhldi ) View more | |||||||
Phase 2/3 | - | nuzbmxvraj(pqzvywzsiv) = qiztvhpuki ugkubylgzk (jpszpalppl ) View more | Positive | 25 Oct 2024 |





