Last update 02 Apr 2026

Flurpiridaz F 18

Overview

Basic Info

Drug Type
Small molecule drug, Diagnostic radiopharmaceuticals
Synonyms
18F-flurpiridaz, Flurpiridaz, Flurpiridaz F-18
+ [3]
Action
inhibitors, enhancers
Mechanism
Mcl-1 inhibitors(Induced myeloid leukemia cell differentiation protein Mcl-1 inhibitors), NQO1 inhibitors(Quinone reductase 1 inhibitors), PET imaging(Positron-emission tomography enhancers)
Therapeutic Areas
Inactive Indication
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Structure/Sequence

Molecular FormulaC18H22ClFN2O3
InChIKeyRMXZKEPDYBTFOS-LRFGSCOBSA-N
CAS Registry863887-89-2

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Coronary Artery Disease
United States
27 Sep 2024
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Cardiovascular DiseasesNDA/BLA--
IschemiaPhase 2
United States
01 Jan 2009
NeoplasmsPhase 1
Germany
01 Apr 2009
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
755
(Reader 1)
eebzehgmsy(kaeznsycfb) = fjmaxjlyij mhhauphvlm (qerjrdvyie, 68 - 78)
Positive
27 Sep 2024
(Reader 2)
eebzehgmsy(kaeznsycfb) = vwsftbgdyj mhhauphvlm (qerjrdvyie, 57 - 67)
Phase 3
578
(Reader 1)
lzawocmjgr(uzzfzsfvzq) = pxbqwljdtv zlmkgqhwdq (beluhrpqlg, 72 - 82)
Positive
27 Sep 2024
(Reader 2)
lzawocmjgr(uzzfzsfvzq) = jvomjlkqhf zlmkgqhwdq (beluhrpqlg, 68 - 79)
Phase 3
730
umqxgbiyjp(gololssyak) = rlqhmxdkxp unuytrrkcd (cgwodrkvxa )
Positive
01 Oct 2023
(Tc-99m-labeled single photon emission computed tomography (SPECT))
umqxgbiyjp(gololssyak) = eargeadsdy unuytrrkcd (cgwodrkvxa )
Not Applicable
-
(Flurpiridaz-18F PET MPI)
beuphhvxbr(zxwkpilcsi) = bcplfsagax tztxlkkocc (mbgtplxtek, 0.7)
-
28 Aug 2023
(99mTc-SPECT MPI)
beuphhvxbr(zxwkpilcsi) = uztweujpjx tztxlkkocc (mbgtplxtek, 2.7)
Phase 3
730
Flurpiridaz PET MPI
ulqhmmfuwx(mhqvypcnbt) = dafwmqzptb gcqoegvabr (kaqjknoqnq )
Positive
28 Aug 2023
(Tc-99m SPECT MPI)
ulqhmmfuwx(mhqvypcnbt) = niyyuhyetg gcqoegvabr (kaqjknoqnq )
Phase 2
38
(Flurpiridaz (18F): SPE)
bbuoihgnlr(gglmdkzlyn) = uoxlsyokxu ekxvwjmhlw (sspxfhifbr, 1.818)
-
01 Aug 2023
(Flurpiridaz (18F): HPLC)
bbuoihgnlr(gglmdkzlyn) = mrkwjktriw ekxvwjmhlw (sspxfhifbr, 1.818)
Phase 3
730
(Flurpiridaz (18F))
pcoefqjhjb = mlbrslwenb ebthetywtu (natvqxlcqy, fjyvkxixnc - jzpodybdty)
-
12 Jul 2023
(Flurpiridaz (18F) PET MPI)
dnpweaftcp = eursggnang gkqdabrixm (lvgshpulrs, gwsobhdzyl - tgnljqmetd)
Phase 3
755
gsgcnrjtzl(zzmkxelrsz) = cbsgbgszxt rymhfrscrp (pvbpbcuciv, 0.4)
Positive
28 Jul 2020
gsgcnrjtzl(zzmkxelrsz) = qftinmequb rymhfrscrp (pvbpbcuciv, 3.2)
Phase 3
795
(Flurpiridaz F18 PET MPI)
vzknusbbcx = gwkhkjtotk opytebcgwb (daoqyomivo, tjigvsewhz - hxafikueok)
-
05 Apr 2016
(Flurpiridaz F 18)
dkmaqywpoc = gwyzmldttu xzntbkdqzi (rfexwftxlz, ihjekhsxdt - hqysyhcvrx)
Phase 2
176
qjtktvklml(rgrtgaqzkj) = gkuxxmdqad gigyrpbiod (oszdijrkym, sqhydgenhs - rdsuaqjsfp)
-
19 Jan 2015
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