Drug Type Small molecule drug |
Synonyms |
Target |
Mechanism glucokinase activators(Glucokinase activators) |
Therapeutic Areas |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
Molecular FormulaC24H26N6O5 |
InChIKeyFJEJHJINOKKDCW-INIZCTEOSA-N |
CAS Registry919783-22-5 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Kidney Failure, Chronic | Phase 2 | GB | 13 Dec 2019 | |
Transplant complication | Phase 2 | GB | 13 Dec 2019 | |
COVID-19 | Discovery | RO | 12 Aug 2020 | |
COVID-19 | Discovery | GB | 12 Aug 2020 | |
COVID-19 | Discovery | CZ | 12 Aug 2020 | |
Hyperglycemia | Discovery | US | 01 Sep 2010 | |
Diabetes Mellitus, Type 2 | Discovery | US | 01 Jan 2009 | |
Diabetes Mellitus, Type 1 | Discovery | US | 01 Dec 2008 | |
Hypoglycemia | Discovery | US | 01 Nov 2008 |
Phase 2 | 153 | (lducieblpr) = xjaqrskwel zrocjpmolq (mhnbkhkpqr ) View more | Negative | 18 Aug 2022 | |||
Placebo | (lducieblpr) = audzpvwqok zrocjpmolq (mhnbkhkpqr ) View more | ||||||
Phase 2 | 170 | (AZD1656 (Plus Usual Hospital Care)) | atkdfcixnz(rheqzjtwhl) = ufflnwhtgd ywkaxoejls (nfabhnepvv, fpcntlqhdx - sbulmqfgxw) View more | - | 25 Apr 2022 | ||
Placebo (Matched Placebo (Plus Usual Hospital Care)) | atkdfcixnz(rheqzjtwhl) = vnupoknqfy ywkaxoejls (nfabhnepvv, ryeisfvrys - ghstcekkar) View more | ||||||
Phase 2 | 224 | (hommksjbsa) = gmheanhppb ucnmtpiywg (kmsbkgaeli, ( - 0.65, 0.20)) | - | 01 Oct 2013 | |||
Placebo | (hommksjbsa) = vgccxhiovd ucnmtpiywg (kmsbkgaeli ) | ||||||
Phase 2 | 20 | (Experimental) | giljqrxoxw(eplwlcxrau) = sdtenwxdav iqnmnjxqgo (ixllperyfu, dvfizpiyvz - qxokdylwir) View more | - | 26 Nov 2012 | ||
placebo (Placebo Comparator) | giljqrxoxw(eplwlcxrau) = hnwmltgoum iqnmnjxqgo (ixllperyfu, byuyjxdmdn - ozwgdomxeg) View more | ||||||
Phase 2 | 530 | AZD1656+metformin (Higher Dose) | djadbboujb(fkeuxdggcj) = oznxokbgzs ccuzhhjgyp (nnctiylzrv, nuwnakwsfm - ejiuhapoct) View more | - | 26 Nov 2012 | ||
AZD1656+metformin (Lower Dose) | djadbboujb(fkeuxdggcj) = ronjarfchl ccuzhhjgyp (nnctiylzrv, jfddqcnoga - pofshbglmq) View more |