Last update 17 Apr 2025

Fibromun

Overview

Basic Info

Drug Type
Antibody fusion proteins
Synonyms
Daromun component l19tnf, Fibromun, Immunoglobulin, anti-(human fibronectin ed-b domain) (synthetic human clone l19 scfv fragment) fusion protein with human tumor necrosis factor .alpha., trimer
+ [7]
Action
inhibitors, modulators
Mechanism
EDB-FN inhibitors(Human fibronectin extra domain B inhibitors), TNF-α modulators(Tumor necrosis factor α modulators)
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
RegulationOrphan Drug (United States), Orphan Drug (European Union)
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Structure/Sequence

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Metastatic Soft Tissue SarcomaPhase 3
Spain
09 Aug 2021
MelanomaPhase 3
Germany
01 Jul 2016
Unresectable MelanomaPhase 2
United States
12 Jul 2024
GlioblastomaPhase 2
United States
22 May 2024
Basal Cell CarcinomaPhase 2
Switzerland
02 Sep 2020
Glioblastoma, IDH-WildtypePhase 2
Switzerland
31 May 2019
Malignant glioma of brainPhase 2
Switzerland
31 May 2019
Advanced Malignant Solid NeoplasmPhase 2
Italy
01 Sep 2007
Colorectal CancerPhase 2
Italy
01 Sep 2007
Breast CancerPhase 1
Germany
16 Jan 2013
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
Recurrent Glioblastoma
IDH-wildtype | MGMT promoter status
20
jcfymoorda(dllghileag) = lmpxdlqzsg quzfkcbwrz (omrpvnuyod )
Positive
08 Sep 2023
Phase 3
118
biwudaugib(oopwykpnmq) = uzgjffoocb tqjktppcaf (kxlqbxkcnv )
-
16 Sep 2021
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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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