Last update 08 Feb 2025

THDBH120

Overview

Basic Info

Drug Type
Synthetic peptide
Synonyms
THDBH-120
Target
GIPR x GLP-1R
Mechanism
GIPR agonists(Gastric inhibitory polypeptide receptor agonists), GLP-1R agonists(Glucagon-like peptide 1 receptor agonists)
Therapeutic Areas
Endocrinology and Metabolic Disease
Active Indication
ObesityDiabetes Mellitus, Type 2
Inactive Indication-
Originator Organization
Dongbao Zixing (Hangzhou) Biomedical Co., Ltd.
Active Organization
Dongbao Zixing (Hangzhou) Biomedical Co., Ltd.Tonghua Dongbao Pharmaceutical Co., Ltd.Tonghua Dongbao Pharmaceutical Co., Ltd.
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Related

5
Clinical Trials associated with THDBH120
CTR20242389
/ RecruitingPhase 1
在中国肥胖受试者中评价注射用THDBH120多次给药的安全性、耐受性、药代动力学特征和初步有效性的随机、双盲、安慰剂对照的Ib期临床试验
[Translation] A randomized, double-blind, placebo-controlled Phase Ib clinical trial to evaluate the safety, tolerability, pharmacokinetic characteristics and preliminary efficacy of multiple doses of THDBH120 for injection in obese Chinese subjects
CTR20241940
/ RecruitingPhase 1
在中国成人2型糖尿病患者中评价注射用THDBH120多次给药的安全性、耐受性、药代动力学和药效动力学的随机、双盲、安慰剂对照的Ib期临床试验
[Translation] A randomized, double-blind, placebo-controlled Phase Ib clinical trial to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of multiple doses of THDBH120 for injection in Chinese adults with type 2 diabetes
NCT06744868
/ CompletedPhase 1
A Single- and Multiple-Ascending Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of THDBH120 Injection in Healthy Subjects: A Randomized, Bouble-Blind, Placebo-Controlled Phase I Trial
100 Clinical Results associated with THDBH120
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100 Translational Medicine associated with THDBH120
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100 Patents (Medical) associated with THDBH120
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100 Deals associated with THDBH120
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
ObesityPhase 2
CN
Dongbao Zixing (Hangzhou) Biomedical Co., Ltd.
05 Dec 2024
Diabetes Mellitus, Type 2Phase 1
CN
Dongbao Zixing (Hangzhou) Biomedical Co., Ltd.
19 Dec 2023
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Clinical Result

Indication
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Regulation

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