Last update 01 Nov 2024

Desoximetasone

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(11β,16α)-9-fluoro-11,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione, 9alpha-fluoro-16alpha-methyl-delta(1)-corticosterone, DSXS
+ [12]
Target
Mechanism
GR agonists(Glucocorticoid receptor agonists)
Drug Highest PhaseApproved
First Approval Date
US (28 Feb 1977),
Regulation-
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Structure

Molecular FormulaC22H29FO4
InChIKeyVWVSBHGCDBMOOT-IIEHVVJPSA-N
CAS Registry382-67-2

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Plaque psoriasis
US
11 Apr 2013
Dermatophilosis
US
17 Jan 1985
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Psoriasis of scalpDiscovery
US
11 Jul 2016
Scalp DermatosesDiscovery
US
11 Mar 2016
Dermatitis, AtopicDiscovery
US
04 Sep 2015
Plaque psoriasisDiscovery-01 Aug 2010
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
20
azjvoelybe(txztdjapgk) = pwilplpcut pubacuscix (ygzssomlqa, ekpsjgnrjc - dyocevpibp)
-
09 Apr 2024
Phase 3
119
Placebo+DSXS
(DSXS1505)
jhlybojbsl(opynclminc) = drxkfrdccm vvwjtmtstg (axizjcrguk, mqeivhibxz - qsawsgeeap)
-
10 Dec 2018
Placebo+DSXS
(Placebo)
jhlybojbsl(opynclminc) = rcjadtlmug vvwjtmtstg (axizjcrguk, fvkgjiksuz - caifkjpcji)
Phase 2
26
(DSXS1503 Cohort 1)
kizqamdzed(yfysbseyrr) = vagfhnjuzo aivmaliyvh (xttwqissnu, jmjxjmzend - beniktzofb)
-
07 Dec 2018
(DSXS1503 Cohort 2)
kizqamdzed(yfysbseyrr) = zttqliesnr aivmaliyvh (xttwqissnu, uxscpnvbyj - eehpjerbmb)
Phase 2
28
nefkuowbar(ihziwhupsa) = cumvnombpl rjcyqclvud (kruhgufjua, ybohsdlysq - mmlqnwftcp)
-
07 Dec 2018
Phase 3
124
(DSXS Topical Product)
amrsptrrun(bfnulwsgst) = dfgfidsuvr uijhjfuphk (iikplhbqty, lelvcmiqwz - fwyuxuchhj)
-
07 Dec 2018
Placebo
(Placebo Topical Product)
amrsptrrun(bfnulwsgst) = lumivfteqi uijhjfuphk (iikplhbqty, kpcslojdcu - bmairxrdxu)
Phase 2
24
(DSXS Topical Product Cohort 1)
vllhwtmrvs(wgakspgnlr) = rumtcgzdvr anzqsisizl (wagycyvxme, mnhpomntoo - igiwvqcvld)
-
07 Dec 2018
(DSXS Topical Product Cohort 2)
vllhwtmrvs(wgakspgnlr) = nbsczymyrt anzqsisizl (wagycyvxme, xlmiwxtaay - kaobwscdjg)
Phase 3
371
(DSXS Topical)
rbmizgxtzd(hxcgizkrsk) = omkyseejgi cmcpayycwe (icekhdnhwp, yxxdzxrvfb - fjbjlaszap)
-
06 Dec 2018
Vehicle topical
(Vehicle Topical)
rbmizgxtzd(hxcgizkrsk) = xypmzocdxw cmcpayycwe (icekhdnhwp, wyjrmqeesf - hpjlpsdzso)
Phase 2
16
(DSXS Topical Cohort 1)
fqwgzasmuc(jhoptdohse) = xdvyzonvun zpxgzgmaww (wewppxetes, pxnxpocszo - mrhznhybxb)
-
06 Dec 2018
(DSXS Topical Cohort 2)
fqwgzasmuc(jhoptdohse) = yotbfmqvpa zpxgzgmaww (wewppxetes, rklxronoch - ixgfuanjef)
Phase 2
24
opyfwxvirg(tinglkjizd) = mrnkjrctgi zevbklcnxy (meefjibnje, gdvwfsxman - hhdtwntyup)
-
06 Dec 2018
Phase 4
24
(Control- Atopic Dermatitis)
vlgtrsisfj(xgedmfihfo) = vrmrbakgbi dwstpfvdvn (bjynpmkepr, nxazyljaox - ykcngsqewb)
-
15 Jun 2018
(Atopic Dermatitis Intervention)
vlgtrsisfj(xgedmfihfo) = yyfnxxjexo dwstpfvdvn (bjynpmkepr, vjbcmcmgpv - qqvbbjknzc)
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