Last update 20 Mar 2025

Salfaprodil

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Nelonemdaz
+ [3]
Target
Action
antagonists
Mechanism
GluN2B antagonists(Glutamate [NMDA] receptor subunit epsilon 2 antagonists)
Inactive Indication
Originator Organization
Active Organization
Drug Highest PhasePhase 3
First Approval Date-
RegulationSpecial Review Project (China)
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Structure/Sequence

Molecular FormulaC15H8F7KNO3
InChIKeyGSLUKHIOWOVLLM-UHFFFAOYSA-N
CAS Registry916214-57-8
View All Structures (2)

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Brain InfarctionPhase 3
South Korea
25 Dec 2021
Reperfusion InjuryPhase 3
South Korea
25 Dec 2021
Ischemic strokePhase 3
China
-
Acute Ischemic StrokePhase 2
China
25 Dec 2020
BurnsPhase 2
South Korea
05 Apr 2020
Heart ArrestPhase 2
South Korea
29 Nov 2018
Hypoxia, BrainPhase 2
South Korea
29 Nov 2018
Myocardial InfarctionPhase 2
United States
-
Spinal Cord InjuriesPhase 2
United States
-
Acute Ischemic StrokeDiscovery
China
25 Dec 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
496
(wuetfmefgn): common odds ratio = 0.95 (95% CI, 0.69 - 1.31)
Negative
28 Jan 2025
Placebo
Phase 3
-
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Positive
11 Dec 2024
placebo
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Phase 2
237
(pqpxfnqmnn) = qlxnlexiey hpuowtsguy (trvucdgwhq )
Positive
19 Sep 2022
Placebo
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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