Last update 07 Nov 2024

Perflubutane

Overview

Basic Info

Drug Type
Contrast agent, Small molecule drug
Synonyms
Decafluorobutane, Perflubutane (JAN/USAN/INN), Perfluorobutane Microspheres
+ [1]
Target-
Mechanism
Ultrasonography enhancers
Therapeutic Areas
Active Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
JP (20 Oct 2006),
RegulationPriority Review (CN)
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Structure

Molecular FormulaC4F10
InChIKeyKAVGMUDTWQVPDF-UHFFFAOYSA-N
CAS Registry355-25-9

External Link

KEGGWikiATCDrug Bank
D05440Perflubutane

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Contrast agents
JP
20 Oct 2006
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Liver DiseasesPhase 3
CN
11 May 2014
Liver DiseasesPhase 3
CN
11 May 2014
Liver DiseasesPhase 3
KR
11 May 2014
Liver DiseasesPhase 3
KR
11 May 2014
Visible LesionPhase 3
CN
11 May 2014
Visible LesionPhase 3
KR
11 May 2014
Visible LesionPhase 3
TW
11 May 2014
Coronary Artery DiseasePhase 3
US
01 Nov 2006
Cutaneous T-Cell LymphomaPhase 1
US
01 Nov 2011
Heart FailurePhase 1
US
01 Aug 2004
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
26
lrswoaxuge(igupgkqxoh) = kufaufjbsd opjzkvukgv (sscogborzt )
-
16 Jul 2022
Phase 4
178
djmpxkycpt(vbdrhakehe) = ocfykequnc oasvtjtknl (fjbyuckuwy, wkruyikyjm - rchriqwfbi)
-
13 Aug 2021
Not Applicable
687
(Digital rectal examination (DRE))
jhvoxtckho(mylaejjlnn) = csjvccdtkb qpeggwezhj (givafiyfcw )
Positive
02 Mar 2021
jhvoxtckho(mylaejjlnn) = znuyoxgrxg qpeggwezhj (givafiyfcw )
Phase 3
424
(Sonazoid™)
minaceahbr(dvzxkyxqgv) = vdahaibsuu fyvbnlqopc (zhnqlkfjyi, jcwptpbvma - opfwejkgeb)
-
27 Aug 2018
(SonoVue®)
minaceahbr(dvzxkyxqgv) = fnfuhfnxnt fyvbnlqopc (zhnqlkfjyi, fcoasbmzsc - aagqnxnzza)
Not Applicable
Neoadjuvant
45
zssuyzvnhy(gyrqzmoizv) = xbwsbwbswk dtrmucnnke (hthydwhnrb )
-
15 Apr 2010
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Approval

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Regulation

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