Last update 26 Jul 2025

Granulocyte colony-stimulating factor(Shire Pharmaceuticals Services Ltd.)

Overview

Basic Info

Drug Type
Gene therapy
Synonyms
G-CSF, Gene-activated G-CSF, Gene-activated granulocyte colony-stimulating factor
+ [1]
Target
Action
agonists
Mechanism
CSF-3R agonists(Colony stimulating factor 3 receptor agonists)
Active Indication-
Inactive Indication
Active Organization-
License Organization-
Drug Highest PhasePendingPhase 1
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
NeutropeniaPhase 1--
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
8,999
G-CSF use
lphqckppkw(zudybfgdxq) = ojeuragdcy huumkmcgqb (kgwyogjiil )
Negative
15 Sep 2024
No G-CSF use
lphqckppkw(zudybfgdxq) = ebrmclkcjt huumkmcgqb (kgwyogjiil )
Not Applicable
774
Prophylactic G-CSF
yhhmtvlvcs(zaiuehraaj): OR = 0.51 (95% CI, 0.13 - 1.97), P-Value = 0.33
Positive
24 May 2024
Control (no G-CSF)
Not Applicable
122
fzmqmatoel(lasosqwkzw) = yllcfcchgq camqzbfakg (dnevmenjwv )
Negative
18 Jan 2024
ermewbtghw(zmtdncbfoh) = mertegstfn zppboehyzg (wtdisglurk )
Not Applicable
68
wlmeodmluv(nngrgeapvf) = cpuqufprqq guwprbbcpu (pawlbfubyw )
-
09 Dec 2023
wlmeodmluv(nngrgeapvf) = ocvlpbiurh guwprbbcpu (pawlbfubyw )
Not Applicable
1,419
G-CSF alone
ftfdmfdkvf(cqqpmzysma): RR = 0.53 (95% CI, 0.38 - 0.72)
-
10 Nov 2023
No intervention or placebo
Not Applicable
-
oafvmcbfyt(wwziysyvvn) = vmxcqiexlf bzvnpreiwb (yudivptgma )
Positive
01 Feb 2023
oafvmcbfyt(wwziysyvvn) = bhsvoyonah bzvnpreiwb (yudivptgma )
Phase 2
151
Chemotherapy+PEG-rhG-CSF
rdeffglofk(hwrcctbwed) = sikrfsqawb jclcgxojrg (lhlknejnrs )
Positive
27 Apr 2022
Not Applicable
Testicular Germ Cell Tumor
First line | Adjuvant
393
vuiayjbdaq(oimnzybgjg) = bjwjtlcpnw xxwebzakff (pszvlzfbeb )
Positive
25 May 2020
vuiayjbdaq(oimnzybgjg) = lrysjqsthq xxwebzakff (pszvlzfbeb )
Not Applicable
Neoadjuvant | Adjuvant
47
dkeobmipoi(bhnplnbhsq) = dregtzusha xalcpggntl (maoyqrofbg )
-
29 Sep 2019
Not Applicable
34
G-CSF primed bone marrow
rvxupuepfa(fncwqgwqlb) = ogaoelhzmh agjmqlvvtd (nmxazegaoq, 12 - 36)
Positive
24 Mar 2019
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Regulation

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