Last update 07 Nov 2024

LX-101(Lirum Therapeutics)

Overview

Basic Info

Drug Type
Peptide drug conjugates
Synonyms
IGF-methotrexate conjugate (IGF Oncology), IGF-MTX, IGF/MTX
+ [2]
Mechanism
FOLR1 antagonists(Folate receptor alpha antagonists), IGF-1 modulators(Insulin-like growth factor I modulators)
Active Indication
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhaseIND Application
First Approval Date-
Regulation-
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Structure

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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Anemia, Refractory, With Excess of BlastsPhase 2
US
21 Feb 2018
Chronic Myelomonocytic LeukemiaPhase 2
US
21 Feb 2018
Brain CancerPhase 1
US
28 Jan 2014
Breast CancerPhase 1
US
28 Jan 2014
Female Genital NeoplasmsPhase 1
US
28 Jan 2014
Gastrointestinal NeoplasmsPhase 1
US
28 Jan 2014
Head and Neck NeoplasmsPhase 1
US
28 Jan 2014
MelanomaPhase 1
US
28 Jan 2014
Thoracic NeoplasmsPhase 1
US
28 Jan 2014
Graves OphthalmopathyIND Application
US
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
2
hqxktfgnvt(ggyreokhee) = bojbazccpr zjiurscqjg (cxdthkslnq, hofqnpqnhs - pslxhxsdwg)
-
21 May 2024
Phase 1
Neoplasms
IGF-1R expression
19
cejbdaiwyv(angfxujlhw) = quyjzszsii mqkbjumpbd (sjzzkailut )
Positive
26 Feb 2024
Phase 1
2
vholwiljek(kedypmqhmx) = from 22% to 5% in one patient, and from 17% to 16% in the other dgcvnauzhn (fxlnqddgeq )
Positive
01 Jul 2020
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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