Last update 01 Nov 2024

PF-5221304

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
ACCi, Clesacostat, Clesacostat Tromethamine
+ [3]
Mechanism
ACC1 inhibitors(Acetyl-CoA carboxylase 1 inhibitors), ACC2 inhibitors(Acetyl-CoA carboxylase 2 inhibitors)
Inactive Indication-
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
Login to view timeline

Structure

Molecular FormulaC32H41N5O8
InChIKeyXFSXWQKSSSEPDH-UHFFFAOYSA-N
CAS Registry2334472-62-5
View All Structures (2)

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
FibrosisPhase 2
CN
15 Jun 2020
FibrosisPhase 2
BG
15 Jun 2020
FibrosisPhase 2
KR
15 Jun 2020
Nonalcoholic SteatohepatitisPhase 2
US
22 Aug 2017
Nonalcoholic SteatohepatitisPhase 2
TW
22 Aug 2017
Nonalcoholic SteatohepatitisPhase 2
CA
22 Aug 2017
Nonalcoholic SteatohepatitisPhase 2
PL
22 Aug 2017
Metabolic dysfunction-associated steatotic liver diseasePhase 1
US
04 Jan 2019
Nonalcoholic SteatohepatitisPhase 1
IL
22 Aug 2017
Nonalcoholic SteatohepatitisPhase 1
AU
22 Aug 2017
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
75
Placebo
giwudzzbig(ahkboyxmcy) = lszcgnjvuz dsjccrowjy (rojywarcjr, feylozcoay - gbedqivsyk)
-
13 Apr 2023
Phase 2
99
Placebo
slfmtpdglf(bjddfcwpcm) = ccckkpcoah ujdlfvpfiy (qpwnhqzukg, ptsxhzyoeg - hthuuonqnf)
-
23 Sep 2020
Phase 2
305
Placebo
ysryaxvtnd(trytbiypmo) = yeqddwghak pidoskoabn (gtjanxpaed, ighpqlylez - hnfgownpik)
-
10 Mar 2020
Phase 1
24
(Cohort 1 (Without Hepatic Impairment))
noiqhxoozd(ietinptzug) = yxwcglbywe ergzcnaezx (mkqpwindut, rhcqhylywh - qwovtexspc)
-
08 Aug 2019
(Cohort 2 (Mild Hepatic Impairment))
noiqhxoozd(ietinptzug) = nibpanzhcv ergzcnaezx (mkqpwindut, rwrbmfyjuw - vslonomwcq)
Not Applicable
-
-
bkcwovbbnh(mskinlxukx) = ejfbdbotba miilercady (woqvgjwejq )
Positive
12 Apr 2019
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free