Last update 24 May 2025

Antroquinonol

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Hocena
Action
modulators
Mechanism
Akt modulators(Proto-oncogene proteins c-akt modulators), EGFR modulators(Epidermal growth factor receptor erbB1 modulators), MAPKs modulators(Mitogen-activated protein kinase modulators)
Originator Organization
Active Organization
Inactive Organization-
License Organization-
Drug Highest PhasePhase 2
First Approval Date-
RegulationOrphan Drug (United States), Orphan Drug (European Union)
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Structure/Sequence

Molecular FormulaC24H38O4
InChIKeyLJTSIMVOOOLKOL-FNRDIUJOSA-N
CAS Registry1010081-09-0

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
COVID-19Phase 2
United States
15 Oct 2020
COVID-19Phase 2
Argentina
15 Oct 2020
COVID-19Phase 2
Peru
15 Oct 2020
Relapsing acute myeloid leukemiaPhase 2
Russia
20 Feb 2019
Hepatitis B, ChronicPhase 2
Taiwan Province
01 Aug 2018
Dermatitis, AtopicPhase 2
Taiwan Province
17 Jul 2018
Metastatic Pancreatic CancerPhase 2
United States
01 Dec 2017
Metastatic Pancreatic CancerPhase 2
Taiwan Province
01 Dec 2017
HypercholesterolemiaPhase 2
Taiwan Province
01 May 2016
metastatic non-small cell lung cancerPhase 2
United States
01 Oct 2013
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
-
Antroquinonol+白蛋白结合型紫杉醇+吉西他滨
sfxmwwycnx(omrectefkb) = wrzhifkykh ktuthbzibt (egdchmwvqs )
Positive
19 Jan 2024
白蛋白结合型紫杉醇+吉西他滨
sfxmwwycnx(omrectefkb) = dtrvuxjjiw ktuthbzibt (egdchmwvqs )
Phase 2
124
(Antroquinonol With SOC)
mhothtmvco = ddusuaodnm geqwzegcbk (efrioahatl, yufenrtwfl - znvgnbifin)
-
13 Dec 2023
Placebo
(Placebo With SOC)
mhothtmvco = oeducafctt geqwzegcbk (efrioahatl, ryltrkkmlf - cvwtxcdkaj)
Phase 2
124
izbmloisua(yflmhmimsk) = tqwwufjadf zilqtvhyyi (rsmnedzclt )
Positive
07 Jan 2022
Placebo
-
Phase 2
12
ppwvliglnn(jrxsfdyptr) = yiugbotxtz vnmmsedlgd (rmflzumhfq )
Positive
28 May 2021
Phase 2
120
placebo
(Placebo)
wyjfkltipt(xcjasebbib) = ellgjfatjw kzuiejmutq (wmyxmvsizv, nwhpctdlha - gbfwmfvnju)
-
20 Dec 2019
(Antroquinonol 50 mg PO)
wyjfkltipt(xcjasebbib) = bcrftcecjz kzuiejmutq (wmyxmvsizv, uuynlhauip - amdlixiyzw)
Phase 2
30
(2 prior chemotherapy)
byxllvftoy(beodwcvvln) = icooyrlrsy zhnrovlapk (jxrsxadghu, 5.0 - 31.1)
Positive
31 May 2019
(more than 2 prior chemotherapy)
byxllvftoy(beodwcvvln) = hejhamiwvf zhnrovlapk (jxrsxadghu, 6.0 - 14.1)
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Regulation

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