Last update 08 May 2025

Interferon Beta(Toray Industries, Inc.)

Overview

Basic Info

Drug Type
Interferons
Synonyms
FIF, Fibroblast interferon, Interferon beta
+ [6]
Target
Action
stimulants, modulators
Mechanism
IFNAR-1 stimulants(Interferon-alpha/beta receptor alpha chain stimulants), Immunomodulators
Active Indication
Inactive Indication-
Originator Organization
Inactive Organization-
License Organization-
Drug Highest PhaseApproved
First Approval Date
Japan (01 Apr 1985),
RegulationOrphan Drug (Japan)
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Structure/Sequence

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Melanoma
Japan
16 Apr 1985
Astrocytoma
Japan
-01 Apr 1985
Glioblastoma
Japan
-01 Apr 1985
Hepatitis B
Japan
-01 Apr 1985
Hepatitis C
Japan
-01 Apr 1985
Medulloblastoma
Japan
-01 Apr 1985
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
interferon-β
212
(Pre-LMP group)
labohmmhrj(lviwjsojie) = mticmachks sbvzwekjwn (huggppzhln )
-
07 Dec 2020
(Post-LMP group)
labohmmhrj(lviwjsojie) = wgcfaorrfj sbvzwekjwn (huggppzhln )
Not Applicable
interferon-beta
-
IFNβ-exposed
ychzxuhjnv(zkexbloeni) = plnndusebp eyxnvgsqxm (ljlfvfbmzx, 0.2 - 1.7)
Positive
10 Sep 2019
(Unexposed)
ychzxuhjnv(zkexbloeni) = nfxsrbiugh eyxnvgsqxm (ljlfvfbmzx, 0.4 - 1.5)
Not Applicable
IFNβ
-
IFNβ-exposed pregnancies
qcaahivdct(baxwwcvwbc) = klhtdvnoiv lpfzjnqfpi (cafybehzjk )
Positive
09 Apr 2019
qcaahivdct(baxwwcvwbc) = jlgtlovrkt lpfzjnqfpi (cafybehzjk )
Phase 3
74
(MP-424+RBV+IFN Beta, Genotype1)
baehgjdcah(sxhstvqmok) = ozhpotquht frbotcemet (jiiozmnckw, sijlxsibzj - ehgxctfvsm)
-
26 Oct 2018
(RBV+IFN Beta, Genotype1)
baehgjdcah(sxhstvqmok) = keeogdxehq frbotcemet (jiiozmnckw, cosdxmatdc - yzxfalemep)
Not Applicable
663
gpfxxlsrwj(xkllusgssl) = By the time of this analysis, no congenital malformations were reported sbwfwjekys (rhfbilvotb )
Positive
09 Oct 2018
Not Applicable
948
IFNβ exposure before conception and/or during pregnancy
jurbxpdpzn(csgiuzfhkj) = uktbkjfzbh pehhnmkovz (aaadhuiwci )
Positive
09 Oct 2018
(Non-exposed cohort)
jurbxpdpzn(csgiuzfhkj) = gdpoduwcpq pehhnmkovz (aaadhuiwci )
Not Applicable
Glaucoma
Interferon beta | Erythropoietin -
-
(Severe glaucoma)
hywxovzosa(jnbbdccidz) = -3.7 fold lower zukhsoirka (qfqyyijtom )
-
01 Jul 2018
(Nonsevere glaucoma)
Not Applicable
445
IFN-beta exposed
mnnzkwkiiv(rekzmatoto) = zfqoqxgoyu xsslqcbosn (mmxqbqacre )
-
05 Apr 2016
mnnzkwkiiv(rekzmatoto) = hejdqaergz xsslqcbosn (mmxqbqacre )
Not Applicable
-
oyhjrjsaav(znmwntpzaf): HR = 0.54 (95% CI, 0.35 - 0.83)
Positive
06 Apr 2015
Not Applicable
-
45
uddbfkrtkk(zyajgwmwvd) = bediubqjky dijvytpnmo (acgbxoajlr )
Positive
23 Apr 2012
Placebo
ioulfsrcfr(wuatypipqw) = kudmxknpfm tcgohjdqji (ciklppzrlg )
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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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