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Last update 24 Mar 2025
Dodekin (Philogen)
Last update 24 Mar 2025
Overview
Basic Info
Drug Type Monoclonal antibody |
Synonyms IL12 L19L19, IL12-L19-L19, IL12-L19L19 + [1] |
Target |
Action inhibitors, stimulants |
Mechanism EDB-FN inhibitors(Human fibronectin extra domain B inhibitors), IL-12R stimulants(Interleukin-12 receptor stimulants) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhasePhase 1 |
First Approval Date- |
Regulation- |
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Related
1
Clinical Trials associated with Dodekin (Philogen)NCT04471987
A Phase I Study to Evaluate Safety and Early Signs of Efficacy of the Human Monoclonal Antibody-cytokine Fusion Protein IL12-L19L19.
100 Clinical Results associated with Dodekin (Philogen)
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100 Translational Medicine associated with Dodekin (Philogen)
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100 Patents (Medical) associated with Dodekin (Philogen)
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100 Deals associated with Dodekin (Philogen)
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Neoplasms | Phase 2 | Switzerland | 27 Apr 2021 | |
| Advanced Malignant Solid Neoplasm | Phase 1 | Germany | 01 Jul 2020 | |
| Advanced Malignant Solid Neoplasm | Phase 1 | Italy | 01 Jul 2020 | |
| Advanced Malignant Solid Neoplasm | Phase 1 | Switzerland | 01 Jul 2020 | |
| Metastatic Solid Tumor | Phase 1 | Germany | 01 Jul 2020 | |
| Metastatic Solid Tumor | Phase 1 | Italy | 01 Jul 2020 | |
| Metastatic Solid Tumor | Phase 1 | Switzerland | 01 Jul 2020 | |
| Diffuse Large B-Cell Lymphoma | Phase 1 | Italy | 21 Jun 2020 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
View All Results
Phase 1 | 20 | disrluotqy(zxjbhbbndu) = One patient in cohort 3 (0.5 μg/kg) developed a DLT (G3 transient AST/ALT increase) xctlvihrsa (hzbkjzhdfo ) View more | Positive | 26 Feb 2024 |
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