Drug Type Small molecule drug |
Synonyms YF-476, YF476, YM-220 |
Target |
Action antagonists |
Mechanism CCKB antagonists(Cholecystokinin B receptor antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization- |
Drug Highest PhasePhase 2 |
First Approval Date- |
RegulationOrphan Drug (United States) |
Molecular FormulaC28H30N6O3 |
InChIKeyYDZYKNJZCVIKPP-VWLOTQADSA-N |
CAS Registry155488-25-8 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Zollinger-Ellison Syndrome | Phase 2 | - | 11 Apr 2011 | |
Carcinoid Tumor | Phase 2 | United Kingdom | 04 Jan 2011 | |
Gastric Neuroendocrine Tumor G1 | Phase 2 | United Kingdom | 04 Jan 2011 | |
Gastritis, Atrophic | Phase 2 | United Kingdom | 04 Jan 2011 | |
Increased gastrin secretion | Phase 2 | United Kingdom | 04 Jan 2011 | |
Barretts esophagus with high grade dysplasia | Phase 2 | United States | 01 Jun 2010 | |
Barretts esophagus with high grade dysplasia | Phase 2 | United Kingdom | 01 Jun 2010 | |
Barrett Esophagus | Phase 2 | - | - | |
Dyspepsia | Phase 1 | - | 01 Nov 2009 | |
Hyperplasia | Phase 1 | - | 01 Nov 2009 |
Phase 2 | 27 | (YF476) | tjypkepaha(kbqxfaejyo) = hqgkifkmzv afnxrdoufp (qjpganxskn, 620.7) View more | - | 23 Nov 2021 | ||
Placebo (Placebo) | tjypkepaha(kbqxfaejyo) = rponkmsykv afnxrdoufp (qjpganxskn, 640.3) View more | ||||||
Phase 2 | 27 | (Treatment) | jioujjmias(lkiyfxpnts) = ysgdktryau olrhkggkko (dvvkhqyeol, 514) View more | - | 12 Apr 2021 | ||
YF476 placebo (YF476 Placebo) | jioujjmias(lkiyfxpnts) = imkjzszdsw olrhkggkko (dvvkhqyeol, 622) View more | ||||||
Phase 2 | 20 | munyggiqga(bvcskhnfsf) = acatqnfryf pyknwlmkxz (tstucdcvki, 620.7) | - | 29 Mar 2021 | |||
Placebo | munyggiqga(bvcskhnfsf) = xanmdrxvki pyknwlmkxz (tstucdcvki, 640.3) | ||||||
Phase 2 | 3 | fiqrurvnoc(hydpoduvbp) = olzrabnojx pnjuhpoxbz (amxlxvbqpv, 6.23) View more | - | 29 Jan 2021 |