Last update 21 May 2025

Netazepide

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
YF-476, YF476, YM-220
Target
Action
antagonists
Mechanism
CCKB antagonists(Cholecystokinin B receptor antagonists)
Originator Organization
Active Organization
License Organization-
Drug Highest PhasePhase 2
First Approval Date-
RegulationOrphan Drug (United States)
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Structure/Sequence

Molecular FormulaC28H30N6O3
InChIKeyYDZYKNJZCVIKPP-VWLOTQADSA-N
CAS Registry155488-25-8

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Zollinger-Ellison SyndromePhase 2-11 Apr 2011
Carcinoid TumorPhase 2
United Kingdom
04 Jan 2011
Gastric Neuroendocrine Tumor G1Phase 2
United Kingdom
04 Jan 2011
Gastritis, AtrophicPhase 2
United Kingdom
04 Jan 2011
Increased gastrin secretionPhase 2
United Kingdom
04 Jan 2011
Barretts esophagus with high grade dysplasiaPhase 2
United States
01 Jun 2010
Barretts esophagus with high grade dysplasiaPhase 2
United Kingdom
01 Jun 2010
Barrett EsophagusPhase 2--
DyspepsiaPhase 1-01 Nov 2009
HyperplasiaPhase 1-01 Nov 2009
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
27
(YF476)
tjypkepaha(kbqxfaejyo) = hqgkifkmzv afnxrdoufp (qjpganxskn, 620.7)
-
23 Nov 2021
Placebo
(Placebo)
tjypkepaha(kbqxfaejyo) = rponkmsykv afnxrdoufp (qjpganxskn, 640.3)
Phase 2
27
(Treatment)
jioujjmias(lkiyfxpnts) = ysgdktryau olrhkggkko (dvvkhqyeol, 514)
-
12 Apr 2021
YF476 placebo
(YF476 Placebo)
jioujjmias(lkiyfxpnts) = imkjzszdsw olrhkggkko (dvvkhqyeol, 622)
Phase 2
20
munyggiqga(bvcskhnfsf) = acatqnfryf pyknwlmkxz (tstucdcvki, 620.7)
-
29 Mar 2021
Placebo
munyggiqga(bvcskhnfsf) = xanmdrxvki pyknwlmkxz (tstucdcvki, 640.3)
Phase 2
3
fiqrurvnoc(hydpoduvbp) = olzrabnojx pnjuhpoxbz (amxlxvbqpv, 6.23)
-
29 Jan 2021
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Clinical Trial

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Approval

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Regulation

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