Last update 19 Jun 2024

Cicletanine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Cicletanine (USAN/INN), cycletanide, BN-1270 (HCl)
+ [5]
Mechanism
α-adrenergic receptor agonists(Alpha adrenergic receptor agonists), β-adrenoceptors agonists(Beta adrenergic receptors agonists)
Therapeutic Areas
Active Indication
Originator Organization
Active Organization
Drug Highest PhaseApproved
First Approval Date
JP (01 Jan 1988),
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC14H13Cl2NO2
InChIKeyQLMBAIRFQQLJJX-UHFFFAOYSA-N
CAS Registry82747-56-6

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hypertension
JP
01 Jan 1988
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetes MellitusPhase 2-01 Jun 2016
HypokalemiaPhase 2-01 Jun 2016
HyponatremiaPhase 2-01 Jun 2016
Pulmonary Arterial HypertensionPhase 2
AU
01 Jan 2009
Pulmonary Arterial HypertensionPhase 2
AT
01 Jan 2009
Pulmonary Arterial HypertensionPhase 2
BE
01 Jan 2009
Pulmonary Arterial HypertensionPhase 2
CA
01 Jan 2009
Pulmonary Arterial HypertensionPhase 2
DE
01 Jan 2009
Pulmonary Arterial HypertensionPhase 2
IL
01 Jan 2009
Pulmonary Arterial HypertensionPhase 2
MX
01 Jan 2009
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
162
iiyelttfyq(qxofczfyhy) = whwxwsbhja cawvvofwlt (nhblhtztmg, -8.0 to 24.0)
Negative
01 Sep 2012
iiyelttfyq(qxofczfyhy) = hmcqledzld cawvvofwlt (nhblhtztmg, -8.0 to 24.0)
Not Applicable
-
68
bbfaumdrnd(zfpjlmmrbf) = Cicletanine-induced hypokalemia occurred in 8 (11.8%) vfmmdfookb (temjkyhzwh )
Positive
01 May 2012
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Regulation

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