Drug Type Small molecule drug |
Synonyms BNP-1051, BNP-1100, BNP-1111 + [9] |
Target |
Action inhibitors |
Mechanism TOP1 inhibitors(DNA topoisomerase I inhibitors) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 3 |
First Approval Date- |
Regulation- |
Molecular FormulaC25H28N2O4Si |
InChIKeyPOADTFBBIXOWFJ-VWLOTQADSA-N |
CAS Registry203923-89-1 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Platinum-Resistant Epithelial Ovarian Carcinoma | Phase 3 | Hungary | 01 Aug 2007 | |
Platinum-Resistant Epithelial Ovarian Carcinoma | Phase 3 | Lithuania | 01 Aug 2007 | |
Platinum-Resistant Epithelial Ovarian Carcinoma | Phase 3 | Poland | 01 Aug 2007 | |
Platinum-Resistant Epithelial Ovarian Carcinoma | Phase 3 | Romania | 01 Aug 2007 | |
Platinum-Resistant Epithelial Ovarian Carcinoma | Phase 3 | Russia | 01 Aug 2007 | |
Malignant melanoma, metastatic | Phase 2 | United States | 01 Mar 2005 | |
Melanoma | Phase 2 | United States | 01 May 2002 | |
Malignant glioma of brain | Phase 2 | United States | 01 Oct 2001 | |
Carcinoma | Phase 1 | United States | 01 May 2004 | |
Recurrent Non-Small Cell Lung Cancer | Phase 1 | United States | 01 May 2004 |
Phase 2 | Recurrent Non-Small Cell Lung Cancer Second line | 55 | gxwipzetts(gyxwvpizkc) = ozcqtcorrk rinkhxlaan (cywgiebayj, 8.5 - 17.0) | - | 01 Jun 2005 | ||
Phase 1 | 32 | nbkynnxjyu(ljsypwsnmu) = nwqsuecyfd joyegdrdik (nmekrfyfjz ) View more | Negative | 01 Jun 2005 |