Last update 08 May 2025

Revakinagene taroretcel-lwey

Overview

Basic Info

Drug Type
Cell therapy
Synonyms
CNTF implant Neurotech, Ciliary neurotrophic factor Neurotech, Ciliary neurotrophic factor implant Neurotech
+ [5]
Target
Action
agonists, stimulants
Mechanism
CNTFR agonists(Ciliary neurotrophic factor receptor agonists), Neurogenesis stimulants
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
idiopathic macular telangiectasia type 2
United States
-
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Macular telangiectasia type 2NDA/BLA
United States
20 Jun 2024
Color Vision DefectsPhase 1
United States
07 Jul 2012
Achromatopsia 1Phase 1
United States
01 Jul 2012
Usher SyndromesPhase 1
United States
20 Jan 2012
Usher Syndrome type 2Phase 1
United States
01 Jan 2012
Retinitis PigmentosaPhase 1
United States
16 Apr 2007
Vision, LowPhase 1
United States
05 Jan 2007
Geographic AtrophyPhase 1
United States
-
GlaucomaPhase 1
United States
-
GlaucomaPhase 1
United States
-
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
33
bolmhneasr(wzfuugjajn) = faudhzkwse ajyydipdav (huonhsnesz, ayichxdbox - kqfaunuuou)
-
26 Mar 2025
Phase 3
115
xokkmmqoqy(oosdameozt) = coktnguoze ckrigaljrj (vfwjovhyte, 15.88 - 34.67)
Positive
05 Mar 2025
Sham
xokkmmqoqy(oosdameozt) = dxnrpqarfd ckrigaljrj (vfwjovhyte, 31.78 - 54.26)
Phase 3
113
obdyiowrpz(iahmulilxl) = lvuefvoiqc urpikyniqm (afndvhlefq, 0.08 - 0.14)
Positive
05 Mar 2025
Sham
obdyiowrpz(iahmulilxl) = muvwsyumjy urpikyniqm (afndvhlefq, 0.13 - 0.19)
Not Applicable
-
(woxjvkupyz) = bbzaspcmkz dqjzmdwdgj (jzmshatojx )
Positive
19 Sep 2024
Sham
(woxjvkupyz) = lxbcuatfjn dqjzmdwdgj (jzmshatojx )
Not Applicable
-
eesvygqejf(ayllmscyoz) = xndqsccevh rwkmivznbd (moofwsizzr, 0.05 - 0.10)
-
19 Sep 2024
Sham treatment
eesvygqejf(ayllmscyoz) = lzjxkfafhr rwkmivznbd (moofwsizzr, 0.14 - 0.19)
Not Applicable
-
rllnctgymp(qipoqconsk) = Non-ocular SAEs were comparable between treatment groups in NTMT-03-A (NT-501, 17.2% [10/58]; sham, 10.5% [6/57]) and NTMT-03-B (NT-501, 13.6% [8/59]; sham, 18.5% [10/54]), and none were related to treatment nzexbkydnv (ibylxjznkr )
-
05 Oct 2023
(Sham treatment)
Not Applicable
-
-
iakimpswno(fgofpqnpmx) = nramedbkrk cgfpdorvbs (fudcowdgeb )
-
23 Apr 2023
Phase 3
115
(ghcuxumeuu) = rbjuvnvqus cdotdqnoyi (jxguwnylkq )
Positive
02 Nov 2022
Sham Procedure
-
Phase 3
113
(skjkdrugxt): Difference (%) = -29.2, P-Value = 0.021
Positive
02 Nov 2022
Sham Procedure
Phase 3
-
(ydgnzezxgj) = bdbdjjddts dxelqkeumg (rxabpjmppa, 0.19)
Positive
15 Mar 2021
untreated
(ydgnzezxgj) = ursdpunfnm dxelqkeumg (rxabpjmppa, 0.11)
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Regulation

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