Drug Type Biosimilar, Monoclonal antibody |
Synonyms Bevacizumab biosimilar, MIL 60, MIL-60 + [1] |
Target |
Mechanism VEGF-A inhibitors(Vascular endothelial growth factor A inhibitors), Angiogenesis inhibitors |
Therapeutic Areas |
Active Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date CN (24 Nov 2021), |
Regulation- |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Fallopian Tube Carcinoma | CN | 04 Mar 2022 | |
Glioblastoma | CN | 04 Mar 2022 | |
Ovarian Cancer | CN | 04 Mar 2022 | |
Primary peritoneal carcinoma | CN | 04 Mar 2022 | |
Uterine Cervical Cancer | CN | 04 Mar 2022 | |
Colorectal Cancer | CN | 24 Nov 2021 | |
Non-Small Cell Lung Cancer | CN | 24 Nov 2021 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Recurrent Lung Non-Squamous Non-Small Cell Carcinoma | Phase 3 | CN | 15 Aug 2017 | |
Recurrent Lung Non-Squamous Non-Small Cell Carcinoma | Phase 3 | CN | 15 Aug 2017 | |
Metastatic Colorectal Carcinoma | Phase 1 | CN | 08 Nov 2016 | |
Metastatic Colorectal Carcinoma | Phase 1 | CN | 08 Nov 2016 |
Phase 3 | 517 | jwvkwnsamf(dnmekslyko) = jgtzakezlj ytkwgujyly (muuwckkxuz ) View more | Positive | 01 Dec 2021 | |||
jwvkwnsamf(dnmekslyko) = rkkregbgiz ytkwgujyly (muuwckkxuz ) View more | |||||||
NCT03196986 (ESMO2021) Manual | Phase 3 | 517 | Paclitaxel+Carboplatin+MIL60 | zgywmdpetv(sodceppjnz) = smbscatrcc ybvhmvlcef (hixsurtjrp ) View more | Similar | 16 Sep 2021 | |
zgywmdpetv(sodceppjnz) = cvfcodxxwb ybvhmvlcef (hixsurtjrp ) View more | |||||||
Pubmed Manual | Phase 1 | - | - | iqyaugomgt(hhxqdtbxcb) = Bevacizumab demonstrated linear PK properties and a concentration-dependent disposition. When comparing the three biosimilars with bevacizumab-EU, the 90% CIs of the ratios for Cmax, AUC0-t, and AUC0-∞ were within 80-125%. The inter-CV ranged from 12.6 to 23.3%. wqvvpsyutl (acowankruk ) View more | Positive | 01 Oct 2018 | |