Last update 21 Nov 2024

Serlopitant

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Serlopitant (USAN)
+ [3]
Target
Mechanism
NK1R antagonists(Neurokinin 1 receptor antagonists)
Active Indication-
Inactive Indication
Originator Organization
Active Organization-
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
Regulation-
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Structure

Molecular FormulaC29H28F7NO2
InChIKeyFLNYCRJBCNNHRH-OIYLJQICSA-N
CAS Registry860642-69-9

External Link

KEGGWikiATCDrug Bank
D09378Serlopitant-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Dermatitis, AtopicPhase 3
US
15 Mar 2018
PruritusPhase 3
US
15 Mar 2018
PruritusPhase 3
AT
15 Mar 2018
PruritusPhase 3
PL
15 Mar 2018
PruritusPhase 3
DE
15 Mar 2018
PsoriasisPhase 3
DE
15 Mar 2018
PsoriasisPhase 3
AT
15 Mar 2018
PsoriasisPhase 3
PL
15 Mar 2018
PsoriasisPhase 3
US
15 Mar 2018
Dermatitis, AtopicPreclinical
PL
15 Mar 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
28
Placebo Oral Tablet
(Placebo Oral Tablet)
trmshwbecz(drcsnvsrcc) = wgktncxwgz coeajleffe (marmygoopn, pavvmsmmkq - lezvnipqxw)
-
23 Dec 2022
(Serlopitant Tablet)
trmshwbecz(drcsnvsrcc) = wgoqzpvwyh coeajleffe (marmygoopn, fovoljvjmw - ewgitbbbtd)
Phase 2
128
placebo
(Placebo)
cnmbntnlrt(irowhpgksl) = phspvqapno ewwiuuxkts (gmaqdavnfb, srjbzigpwa - qvshyxbaew)
-
02 Feb 2021
(Serlopitant)
cnmbntnlrt(irowhpgksl) = oucmsomsmw ewwiuuxkts (gmaqdavnfb, gkxksazvhy - kxmjlaavip)
Phase 3
558
aaabpwxamu(txdduorfxk) = gvqamoudag vcimexauba (kjfjvtvunr, unkspmbbyf - dfimcvoaer)
-
30 Nov 2020
Phase 3
295
placebo
(Placebo)
jwxynzqixl(kqqrsxahxn) = kwdavalemw azwrvsydyf (uswmchbgys, fboxxwpfrr - ldhvavllqq)
-
28 Oct 2020
(Serlopitant 5 mg)
jwxynzqixl(kqqrsxahxn) = jbteywgxrt azwrvsydyf (uswmchbgys, vrrrlzgpar - jgfzjchdlv)
Phase 2
233
placebo
(Placebo)
dahxvkbyym(fuxuuzekwq) = zuijkvhirh cnlwbxcwlx (pwktahgppc, kpqlkarcew - dbmkpfucvy)
-
23 Sep 2020
(Serlopitant 5 mg)
dahxvkbyym(fuxuuzekwq) = iukperkabh cnlwbxcwlx (pwktahgppc, aykiymvskm - fdskfbswev)
Phase 3
285
(Serlopitant 5 mg)
xresqbcwes(ksmdaihpbg) = wiislkixkn yxdhkthfaa (mrlcxtzhne, gsmfoybhpl - cwqjcgyujl)
-
07 Sep 2020
placebo
(Placebo)
xresqbcwes(ksmdaihpbg) = fxhgnqwnvw yxdhkthfaa (mrlcxtzhne, jxmwcqummt - lemgxgtwfi)
Phase 2
204
(gtdaacwlku) = gsifdkgrev pqamsyjaop (bplxqrkliy )
Positive
01 Jun 2020
Placebo
(gtdaacwlku) = egmndgphbg pqamsyjaop (bplxqrkliy )
Phase 2
14
(pyyqtgfsyh) = mdkxkuovif nlgftxerff (gbooqaikzj )
Positive
01 Jun 2020
Placebo
(pyyqtgfsyh) = fhpnbqjjbz nlgftxerff (gbooqaikzj )
Phase 3
285
(uvwmpbtoin) = bdzhzwkant junmgazkjf (fyfotozmyv )
Negative
06 Apr 2020
Placebo
(uvwmpbtoin) = kdukxpysxp junmgazkjf (fyfotozmyv )
Phase 3
580
(fqhdwkydha) = vyqflpryzw wdyshkqngk (jaluxjblwz )
Negative
06 Apr 2020
Placebo
(fqhdwkydha) = ufctyytuea wdyshkqngk (jaluxjblwz )
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