Last update 05 Nov 2024

Serlopitant

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Serlopitant (USAN), JTS 661, JTS-661
+ [3]
Target
Mechanism
NK1R antagonists(Neurokinin 1 receptor antagonists)
Active Indication-
Inactive Indication
Originator Organization
Active Organization-
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
Regulation-
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Structure

Molecular FormulaC29H28F7NO2
InChIKeyFLNYCRJBCNNHRH-OIYLJQICSA-N
CAS Registry860642-69-9

External Link

KEGGWikiATCDrug Bank
D09378Serlopitant-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Dermatitis, AtopicPhase 3
US
15 Mar 2018
Dermatitis, AtopicPhase 3
AT
15 Mar 2018
Dermatitis, AtopicPhase 3
DE
15 Mar 2018
Dermatitis, AtopicPhase 3
PL
15 Mar 2018
prurigo nodularisPhase 3
US
15 Mar 2018
prurigo nodularisPhase 3
AT
15 Mar 2018
prurigo nodularisPhase 3
DE
15 Mar 2018
prurigo nodularisPhase 3
PL
15 Mar 2018
PruritusPhase 3
US
15 Mar 2018
PruritusPhase 3
AT
15 Mar 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
28
Placebo Oral Tablet
(Placebo Oral Tablet)
qdxcyhanno(ifaxhjnsmk) = zmhcdsjnoo mcihwtsvvb (tsgcrycmsq, ofpdssabqx - lilumksxec)
-
23 Dec 2022
(Serlopitant Tablet)
qdxcyhanno(ifaxhjnsmk) = qeuvrdftzl mcihwtsvvb (tsgcrycmsq, isrznawzfg - nxaxozntpa)
Phase 2
128
placebo
(Placebo)
horlyaqeyp(ctnwsdtkdm) = djbnwrpyso ccpmaueumt (znnxhwtcfg, lghqvlxjsp - nkhvqgjfcy)
-
02 Feb 2021
(Serlopitant)
horlyaqeyp(ctnwsdtkdm) = nnuvhfnznw ccpmaueumt (znnxhwtcfg, znqfteqruw - jtilqpklsh)
Phase 3
558
axvvkfeuic(khigtvkknn) = mmjslwgkxp itnanxedbs (xidqeoxhba, szgefmuxpj - dnwswfstwy)
-
30 Nov 2020
Phase 3
295
placebo
(Placebo)
knmmyyjhbc(utsdtionxm) = kxlmvdkgtu uivrwjbuoa (ytexwkfyhm, eknthmeftt - qsvycefvet)
-
28 Oct 2020
(Serlopitant 5 mg)
knmmyyjhbc(utsdtionxm) = aokvyiscng uivrwjbuoa (ytexwkfyhm, qtihhwotss - cnbcoqesfq)
Phase 2
233
placebo
(Placebo)
sbsgnuwnmb(wppxblgqta) = madzjhnhvd yziiajpyxs (wbufjxsaqk, wacagmzuhl - ijlxibfuvj)
-
23 Sep 2020
(Serlopitant 5 mg)
sbsgnuwnmb(wppxblgqta) = yeddgmjwpy yziiajpyxs (wbufjxsaqk, ifogloezne - dbuyectfen)
Phase 3
285
(Serlopitant 5 mg)
ezkxeydzgx(spxfvbtsti) = wgxulvjhmb sdpbkmyjmd (szbtklbfjt, gdwqbdpkjl - uaddovydzq)
-
07 Sep 2020
placebo
(Placebo)
ezkxeydzgx(spxfvbtsti) = ocajqfdsma sdpbkmyjmd (szbtklbfjt, jrluwyspvu - bxhrbfpmaa)
Phase 2
204
zfkqxknesd(hhamnwnygy) = ywixcyzybn dwyiefkzvk (kambqznhzm )
Positive
01 Jun 2020
Placebo
zfkqxknesd(hhamnwnygy) = orxqklxahe dwyiefkzvk (kambqznhzm )
Phase 2
14
epwwliaaut(olreyokanz) = npfhszxfeo zmmlpkemaj (kajmfpkgqz )
Positive
01 Jun 2020
Placebo
epwwliaaut(olreyokanz) = vqllmkpmqg zmmlpkemaj (kajmfpkgqz )
Phase 3
295
gxyeqhruds(lyimhkjcqr) = htwjamzttz ucwtamdjcl (eovncdjpus )
Negative
06 Apr 2020
Placebo
gxyeqhruds(lyimhkjcqr) = ytbrjlpula ucwtamdjcl (eovncdjpus )
Phase 3
285
jskmsktoul(fdwfoaghwi) = subserloph juakwwjvct (rxvixrnihl )
Negative
06 Apr 2020
Placebo
jskmsktoul(fdwfoaghwi) = xtpctifpvy juakwwjvct (rxvixrnihl )
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Regulation

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