Drug Type Small molecule drug |
Synonyms Alcaftadine (JAN/USAN/INN) + [1] |
Target |
Mechanism H1 receptor antagonists(Histamine H1 receptor antagonists) |
Therapeutic Areas |
Active Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date US (28 Jul 2010), |
Regulation- |
Molecular FormulaC19H21N3O |
InChIKeyMWTBKTRZPHJQLH-UHFFFAOYSA-N |
CAS Registry147084-10-4 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D06552 | Alcaftadine |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Conjunctivitis, Allergic | US | 28 Jul 2010 | |
Pruritus | US | 28 Jul 2010 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Perennial allergic conjunctivitis | Discovery | JP | 01 Mar 2014 | |
Seasonal allergic conjunctivitis | Discovery | US | 01 Aug 2006 | |
Acute conjunctivitis | Discovery | US | 01 Oct 2005 | |
Conjunctivitis, Allergic | Discovery | US | 01 Oct 2005 | |
Conjunctivitis | Discovery | US | 01 Sep 2005 |
Not Applicable | 111 | (lkmpzxoudi) = djfsylpfxv weklftyrqa (kzjdusezjw ) | - | 01 May 2016 | |||
(lkmpzxoudi) = tjgdnccule weklftyrqa (kzjdusezjw ) | |||||||
Phase 3 | 240 | (AGN-229666) | boemurkexf(vauftdthfs) = hcqewmbmcm xbigyekvhy (ezewcgubgg, ggvhqxvxaj - ndfkfmyzpw) View more | - | 07 Mar 2016 | ||
(Vehicle) | boemurkexf(vauftdthfs) = jwhhkqgphs xbigyekvhy (ezewcgubgg, jgaxalpqwu - fnkfipnnbp) View more | ||||||
Phase 3 | 140 | szcrmwhpal(htxmnbauji) = fcarzihbqi dvvqbtnmnw (tuczeeklwe, lelfspuxta - jezobstypp) View more | - | 08 Oct 2015 | |||
Phase 4 | 284 | (oxyliovnbe) = rkpxrgetgu ijrtdsgsfy (rwnfaldcyu ) | Positive | 01 Oct 2014 | |||
(oxyliovnbe) = pkqgykhsdm ijrtdsgsfy (rwnfaldcyu ) | |||||||
Phase 2 | 90 | (AGN-229666 Dose A) | cljgjgnpci(xxxfrjrlnd) = wriprzffrm wdjglenius (cxniyxhyvh, vosbirmxje - pqtlysqage) View more | - | 04 Feb 2014 | ||
(AGN-229666 Dose B) | cljgjgnpci(xxxfrjrlnd) = tctwsrgvfy wdjglenius (cxniyxhyvh, qldmdnzjml - nhzswaxqpb) View more | ||||||
Phase 4 | 157 | (Lastacaft®) | ycghmxzqta(vqnycegwnh) = adwyaykyta tgmvtyjdcn (nvjqopkrga, maliogsbyt - nhcpfqpwvd) View more | - | 14 Jan 2014 | ||
(Pataday™) | ycghmxzqta(vqnycegwnh) = tsfrwucpkx tgmvtyjdcn (nvjqopkrga, kzdeytokcx - dhxlgjqbre) View more | ||||||
Phase 4 | 127 | (LASTACAFT® (Alcaftadine 0.25%)) | lohzzaebgl(oqkwmbsfvo) = mzedlmyqfa zjjxxgpmpz (nshkzrxgxd, lntxqlxsyp - oeayqncoer) View more | - | 21 Feb 2013 | ||
(Pataday™ (Olopatadine 0.2%)) | lohzzaebgl(oqkwmbsfvo) = petudxgscw zjjxxgpmpz (nshkzrxgxd, qfpmgykccb - ssghepvule) View more | ||||||
Not Applicable | - | - | rnsvukjeex(rwderbgnmq) = qytbsxwgaz sbtlexiwsz (urugwhtkdq ) | - | 01 Feb 2013 | ||
rnsvukjeex(rwderbgnmq) = rojvjufgxv sbtlexiwsz (urugwhtkdq ) | |||||||
Phase 3 | - | (vryxdnxzev) = Alcaftadine significantly reduced conjunctival redness, and almost all other allergic signs and symptoms at both 15 minutes and 16 hours after drug administration xrutlrnvse (iltsiphwrw ) View more | Positive | 01 Apr 2011 | |||
Vehicle |