Last update 20 Mar 2025

Uzatresgene autoleucel

Overview

Basic Info

Drug Type
TCR-T Cell therapy
Synonyms
Autologous genetically modified ADP-A2M4CD8 cells, uza-cel
Target
Action
inhibitors
Mechanism
MAGEA4 inhibitors(Melanoma-associated antigen 4 inhibitors)
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Recurrent ovarian cancerPhase 2
France
26 Jun 2023
Advanced Gastroesophageal Junction AdenocarcinomaDiscovery
United States
15 Sep 2021
Advanced Gastroesophageal Junction AdenocarcinomaDiscovery
Spain
15 Sep 2021
Advanced Gastroesophageal Junction AdenocarcinomaDiscovery
Canada
15 Sep 2021
Esophageal CarcinomaDiscovery
Canada
15 Sep 2021
Esophageal CarcinomaDiscovery
United States
15 Sep 2021
Esophageal CarcinomaDiscovery
Spain
15 Sep 2021
Gastrooesophageal junction cancerDiscovery
Canada
15 Sep 2021
Gastrooesophageal junction cancerDiscovery
Spain
15 Sep 2021
Gastrooesophageal junction cancerDiscovery
United States
15 Sep 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
7
(ecgarwingm) = Adverse events have been consistent with those typically observed with lymphodepletion chemotherapy or cellular therapy mwvaisefuy (bkvqlfksxq )
Positive
21 Feb 2023
Phase 1
13
(gedshqogwk) = tqbtrrdxsi btwakoezhy (lkggzbwitz )
Positive
24 Jan 2023
Phase 1
29
(ewomtkpawz) = qnerdvvlbw rvyvhmybpp (korarluvrl )
-
10 Sep 2022
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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