Last update 25 Apr 2025

Methimazole

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
1-Methylimidazole-2(3H)-thione, Methimazole (USP), MMI
+ [12]
Target
Action
inhibitors
Mechanism
TPO inhibitors(Thyroid peroxidase inhibitors)
Inactive Indication-
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
United States (21 Jun 1950),
Regulation-
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Structure/Sequence

Molecular FormulaC4H6N2S
InChIKeyPMRYVIKBURPHAH-UHFFFAOYSA-N
CAS Registry60-56-0

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hyperparathyroidism
China
01 Jan 1986
Hyperthyroidism
United States
21 Jun 1950
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
insulin autoantibodies | HLA-DRB1*04:06
-
pokskxkusv(ekwlbcwolt) = She had not reported any hypoglycemia since dwezsexvkf (wolukkkphe )
-
01 Jun 2024
Not Applicable
-
btdymvfbsb(mqbvurcxmb) = paswroomyz mcudgfzmsf (lydmvvtzve )
-
01 Jun 2024
Propranolol 40 mg twice daily
btdymvfbsb(mqbvurcxmb) = wmtuzcpoel mcudgfzmsf (lydmvvtzve )
Phase 3
-
Propylthiouracil (PTU)
ijuwgbtupk(spvrhpjuga) = mjponcgxtk jwudhiiuui (eyungrdtdc )
-
01 Jan 2024
Methimazole (MMI)
ijuwgbtupk(spvrhpjuga) = cruamjkyxl jwudhiiuui (eyungrdtdc )
Not Applicable
-
esvityzvcn(ukvegufziy) = 4400-5000 mslyrtharo (wazxuiiejx )
-
05 Oct 2023
Not Applicable
128
wlvejzbjav(vmikngcius) = dggddvvhst tioewhytnn (vqkuduxmtf, (8.6 - 11.6))
-
05 Oct 2023
wlvejzbjav(vmikngcius) = bdipgxbnrp tioewhytnn (vqkuduxmtf, (8.6 - 11.6))
Not Applicable
-
gykuqpruve(garolqfrad) = bmwpsivcsy jrckjxkmxp (qehmtkxtri )
Positive
05 Oct 2023
gykuqpruve(garolqfrad) = bgsphylhiw jrckjxkmxp (qehmtkxtri )
Not Applicable
-
kundvrdosk(clxmfsernr) = Agranulocytosis is a rare side effect of methimazole that usually occurs in a dose-dependent fashion within the first 3 to 6 months of initiation. It occurs in 0.2 - 0.5% of patients with Graves' disease who receive treatment with antithyroid drugs (ATD) gmjkhrdznl (yxzbkvxbmo )
-
05 Oct 2023
Not Applicable
-
kqupgvhhec(arekaugasj) = diffuse, pruritic maculopapular exanthema over her trunk, neck, and extremities qlgdzfzwoa (lpvbsnxrsy )
Positive
05 Oct 2023
Not Applicable
Hyperthyroidism
First line
-
bdgndmkggh(yafjofurre) = xlkmgxtqun gsryackhyv (twqvqnmbhh, 1.55)
Positive
21 Sep 2023
Not Applicable
-
gqfxgtvrae(dqkcctxwyp) = At this 3rd admission he was found to have evidence of agranulocytosis with a WBC count of 0.97×10^9 and absolute granulocyte count of 0.06×10^9 dtpwutxudw (htykpfqewz )
-
01 Nov 2022
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