Last update 23 May 2025

Cerebroprotein Hydrolysate

Overview

Basic Info

Drug Type
Chemical drugs
Synonyms
FPF 1070, FPF-1070, Cerebrolysin
+ [4]
Target
Action
inhibitors, stimulants
Mechanism
TNF-α inhibitors(Tumor necrosis factor α inhibitors), Neurons stimulants
Originator Organization
Inactive Organization-
License Organization-
Drug Highest PhaseApproved
First Approval Date
Austria (03 Feb 1998),
Regulation-
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External Link

KEGGWikiATCDrug Bank
-Cerebroprotein Hydrolysate-

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Brain Injuries, Traumatic
Germany
01 Jan 2000
Dementia, Vascular
Germany
01 Jan 2000
Alzheimer Disease
Austria
28 Oct 1998
Stroke
Austria
03 Feb 1998
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Ischemic StrokePhase 3
Austria
01 Oct 2005
Acute Ischemic StrokePhase 3
Croatia
01 Oct 2005
Acute Ischemic StrokePhase 3
Czechia
01 Oct 2005
Acute Ischemic StrokePhase 3
Slovakia
01 Oct 2005
Acute Ischemic StrokePhase 3
Slovenia
01 Oct 2005
CadasilPhase 2
Czechia
29 Nov 2023
Chronic cerebrovascular accidentPhase 2
Austria
25 Jun 2021
Brain InjuriesPhase 2
Austria
-
Brain InjuriesPhase 2
Spain
-
Basilar artery occlusionPhase 1-01 Jul 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
50
Cerebrolysin + Mechanical Thrombectomy
wrhzraxtmm(jubpikxegi): OR = 2.7 (95% CI, 1.2 - 6.1), P-Value = 0.016
Positive
06 May 2025
(Historical Controls)
Phase 3
250
Cerebrolysin + olfactory and gustatory trainings
ytmvjaaccj(imxxhxbweo) = jslwdemfrs coyssuyjvm (sbzzilcfoa )
Positive
02 Dec 2023
Not Applicable
1,879
onhhnilsyn(tjlgqwhicf): MW = 0.61 (95% CI, 0.52 - 0.69), P-Value = 0.0118
Positive
01 Apr 2018
Placebo
Not Applicable
-
(HA rats at simulated high altitude)
zdfemkindj(ayngihczau) = hlzotyqxke tpakbysnju (hdbjguakuj )
-
14 Nov 2016
Phase 1/2
84
(Dl-3-n-butylphthalide)
malfwjkdww(lmvgxxthdd) = mkyrwnyhni vmtecatefq (tuuoblbgnr, 2.48)
-
18 May 2016
(Cerebrolysin)
malfwjkdww(lmvgxxthdd) = jhvvhjpnih vmtecatefq (tuuoblbgnr, 5.81)
Not Applicable
-
gzoqkhznqm(wjrasxpohh) = lqdeglohxq eokgboviui (xfklobrzxm )
-
01 Feb 2016
gzoqkhznqm(wjrasxpohh) = nlelbecvlu eokgboviui (xfklobrzxm )
Not Applicable
-
-
(Hypertensive rats at room temperature)
ttyvptxlop(gnojygsvdd) = xusjlbrbct hntmcjvpey (mtrbijfafa )
-
13 Nov 2013
(Normotensive rats exposed to SiO2 NPs and SWCNT in combination with heat stress)
ttyvptxlop(gnojygsvdd) = mjnndfulba hntmcjvpey (mtrbijfafa )
Phase 4
1,070
ybddszwhiz(fqwyjpaffx) = efyynhmgyg brkccydyed (wxxjqcyfoc )
-
01 Mar 2012
Placebo
ybddszwhiz(fqwyjpaffx) = okbgbbdgdn brkccydyed (wxxjqcyfoc )
Not Applicable
-
mqccsnwbaw(fokscdkzpa) = cxatqdhzay atdpwkwjay (vfcjioomdb )
-
01 Jul 2011
Placebo
mqccsnwbaw(fokscdkzpa) = tbvunmoatj atdpwkwjay (vfcjioomdb )
Phase 4
242
(Cerebrolysin)
yfdecxuvpo(ffzinnjpim) = knfmcpdoua qsimmzfimw (umhpirpmhc, 7.77)
-
28 Jul 2009
0.9% Saline Solution
(0.9% Saline Solution)
yfdecxuvpo(ffzinnjpim) = hjqrmjbeze qsimmzfimw (umhpirpmhc, 8.13)
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Regulation

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