Last update 04 Jul 2026

Mosliciguat

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
BAY 1237592, BAY-1237592, BAY1237592
Target
Action
stimulants
Mechanism
sGC stimulants(Soluble guanylate cyclase stimulants)
Originator Organization
Inactive Organization
Drug Highest PhasePhase 2
First Approval Date-
RegulationOrphan Drug (Japan)
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Structure/Sequence

Molecular FormulaC41H36ClF3N2O5
InChIKeyHFCWZVGKWGOBKV-QNGWXLTQSA-N
CAS Registry2231749-54-3

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Familial Hypersensitivity PneumonitisPhase 2
United States
29 Oct 2024
FibrosisPhase 2
United States
29 Oct 2024
Hypertension, PulmonaryPhase 2
United States
29 Oct 2024
Idiopathic Interstitial PneumoniasPhase 2
United States
29 Oct 2024
Vascular DiseasesPhase 2
United States
29 Oct 2024
Pulmonary hypertension due to interstitial lung diseasePhase 2--
Chronic thromboembolic pulmonary hypertensionPhase 1
Austria
21 Jan 2019
Chronic thromboembolic pulmonary hypertensionPhase 1
Czechia
21 Jan 2019
Chronic thromboembolic pulmonary hypertensionPhase 1
Germany
21 Jan 2019
Chronic thromboembolic pulmonary hypertensionPhase 1
Poland
21 Jan 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
Hypertension, Pulmonary
NO-nonresponsive pts with PVR≥5 Wood units
38
niauremutt(yuiqxmpcmq) = n=2; 5.3% qwiiqnglvo (bpxwmkqpsh )
Positive
16 May 2025
Phase 1
38
ovutknsjvh(rsxtarmfou) = nudwhvoiuh vrixjszmsb (vlgmphrydh )
Positive
10 Sep 2024
ovutknsjvh(rsxtarmfou) = fdtlalmgii vrixjszmsb (vlgmphrydh )
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Core Patent

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Clinical Trial

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Approval

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Regulation

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