Last update 01 Nov 2024

OriCAR-017

Overview

Basic Info

Drug Type
Autologous CAR-T
Synonyms
Chimeric antigen receptor (CAR)-T cell therapy targeting G protein-coupled receptor class-C group-5 member-D (GPRC5D)., GPRC5D-CAR-T, anti-GPCR5D CAR T-cell therapy(Origincell Therapeutics)
+ [2]
Target
Mechanism
GPRC5D inhibitors(G-protein coupled receptor family C group 5member D inhibitors), Immunologic cytotoxicity, T lymphocyte replacements
Active Indication
Inactive Indication-
Originator Organization
Inactive Organization
Drug Highest PhasePhase 1/2
First Approval Date-
RegulationFast Track (US), Orphan Drug (US)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Multiple MyelomaPhase 2
CN
26 Oct 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
10
(hisixykvyg) = ekbfrkrgry ezceklyjfr (kgxdpszjsx )
Positive
24 May 2024
(hisixykvyg) = nxssobwowh ezceklyjfr (kgxdpszjsx )
Phase 1
13
(xaolncfass) = not identified cgglqxisqn (ofcakniezt )
Positive
01 Feb 2024
Early Phase 1
10
(zijhysfnic) = ylhleoxhuk delivmtqvl (cxtdixjmbl )
Positive
30 Jan 2023
(relapsed after BCMA CAR T-cell therapy)
(upvwaenrfk) = bszoeymxal dxsdvghzqn (qxncuajnyd )
Phase 1
11
OriCAR-017+Chemotherapy
(ykyjwavvzg) = The most common TEAEs were neutropenia (G3/4 100%), thrombocytopenia (G3/4 100%), leukopenia (G3/4 100%), lymphopenia (G3/4 100%) and anemia (G3/4 87.5%). oniimzuhys (cawqgamfui )
Positive
02 Jun 2022
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Approval

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Regulation

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