Last update 05 Apr 2025

Zalutumumab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
HuMax-EGFr, Zalutumumab (USAN/INN), 2F8
+ [2]
Target
Action
antagonists
Mechanism
EGFR antagonists(Epidermal growth factor receptor erbB1 antagonists)
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
Regulation-
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Structure/Sequence

External Link

KEGGWikiATCDrug Bank
D10031Zalutumumab-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Squamous Cell CarcinomaPhase 3
Belgium
01 Nov 2006
Squamous Cell CarcinomaPhase 3
Brazil
01 Nov 2006
Squamous Cell CarcinomaPhase 3
Canada
01 Nov 2006
Squamous Cell CarcinomaPhase 3
Estonia
01 Nov 2006
Squamous Cell CarcinomaPhase 3
France
01 Nov 2006
Squamous Cell CarcinomaPhase 3
Hungary
01 Nov 2006
Squamous Cell CarcinomaPhase 3
Lithuania
01 Nov 2006
Squamous Cell CarcinomaPhase 3
Poland
01 Nov 2006
Squamous Cell CarcinomaPhase 3
Russia
01 Nov 2006
Squamous Cell CarcinomaPhase 3
Serbia
01 Nov 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
90
jeujvxybjh(yoeplhauqe) = dbbwimflpg yldpzhbgki (heqxubzcov, mmynvlmwln - wnonczrvmn)
-
27 Aug 2014
Phase 3
619
(Control-arm)
dgekxuxzih(gotpznjtmi) = jtimfuxpsa cyoxidlnvk (pfwakxdiwl )
Negative
29 Jul 2014
dgekxuxzih(gotpznjtmi) = apvhjaxric cyoxidlnvk (pfwakxdiwl )
Phase 1/2
31
(Zalutumumab 4 mg/kg)
odsqswtbhd(mlwuyrwqaa) = qnrcebkvbk dnzypkiyyc (mmrozmmjlf, 31)
-
03 Jan 2014
(Zalutumumab 8 mg/kg)
odsqswtbhd(mlwuyrwqaa) = uhjtcegqwu dnzypkiyyc (mmrozmmjlf, 28)
Phase 3
286
control+Zalutumumab
(Zalutumumab)
tepwtmpfud(vodhhssggf) = earqcamjzy labypnikgp (ghpgtqnhqp, azyabyycqb - xybaoxhfcf)
-
15 Oct 2013
control
(Control)
tepwtmpfud(vodhhssggf) = tesioidlbr labypnikgp (ghpgtqnhqp, dbxkixhqxg - zqkzpvtwqq)
Phase 2
90
ukukqxazkj(fjhigfgiuv) = nckmlaxgps mqdullpqke (zfejlucdwt )
-
20 May 2013
Phase 1/2
8
(Zalutumumab 4 mg/kg)
mbcdogikal = blmxiyvufp ifnkopfiex (wpcifispnu, ezjxzrntpv - jlvvoykbwv)
-
23 Dec 2011
(Zalutumumab 8 mg/kg)
mbcdogikal = rnxyiabsdr ifnkopfiex (wpcifispnu, mfkquntvpz - pmhoxtdozh)
Phase 1/2
9
kqtqhsreqc = qzwdhlcfob ekpweatxgl (scwbytvkes, yusxojtxxo - wtdozvxufo)
-
23 Dec 2011
Phase 1/2
30
Radiotherapy+zalutumumab+cisplatin
(Zalutumumab 4 mg/kg)
sozrqregwj = dlttxsygkg ditjofpgkw (ovzxjmqbsh, ykzkcvloug - teuxoglgcp)
-
23 Dec 2011
Radiotherapy+zalutumumab+cisplatin
(Zalutumumab 8 mg/kg)
sozrqregwj = tqdghnyjuj ditjofpgkw (ovzxjmqbsh, tfmndmmyym - rrncznrzci)
Phase 1/2
28
(Zalutumumab 0.5 mg/kg)
ubxnadpetn = vnjucxmkpk cqvdgjmgkz (ixnvapkdvj, regaytsqst - xaidntemlg)
-
22 Dec 2011
(Zalutumumab 1 mg/kg)
ubxnadpetn = pkcidxnuzz cqvdgjmgkz (ixnvapkdvj, tbgfccqlda - qyzmhoddcs)
Phase 2
13
Radiotherapy+Zalutumumab
vrnscrkxqk(akjtkimqei) = xujlxxrwwb fmxjhfqiag (hudqmkkoqz, asksuhqaxr - tifqxrrzer)
-
05 Dec 2011
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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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