Drug Type Monoclonal antibody |
Synonyms HuMax-EGFr, Zalutumumab (USAN/INN), 2F8 + [2] |
Target |
Action antagonists |
Mechanism EGFR antagonists(Epidermal growth factor receptor erbB1 antagonists) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 3 |
First Approval Date- |
Regulation- |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D10031 | Zalutumumab | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Squamous Cell Carcinoma | Phase 3 | Belgium | 01 Nov 2006 | |
Squamous Cell Carcinoma | Phase 3 | Brazil | 01 Nov 2006 | |
Squamous Cell Carcinoma | Phase 3 | Canada | 01 Nov 2006 | |
Squamous Cell Carcinoma | Phase 3 | Estonia | 01 Nov 2006 | |
Squamous Cell Carcinoma | Phase 3 | France | 01 Nov 2006 | |
Squamous Cell Carcinoma | Phase 3 | Hungary | 01 Nov 2006 | |
Squamous Cell Carcinoma | Phase 3 | Lithuania | 01 Nov 2006 | |
Squamous Cell Carcinoma | Phase 3 | Poland | 01 Nov 2006 | |
Squamous Cell Carcinoma | Phase 3 | Russia | 01 Nov 2006 | |
Squamous Cell Carcinoma | Phase 3 | Serbia | 01 Nov 2006 |
Phase 2 | 90 | jeujvxybjh(yoeplhauqe) = dbbwimflpg yldpzhbgki (heqxubzcov, mmynvlmwln - wnonczrvmn) View more | - | 27 Aug 2014 | |||
Phase 3 | 619 | (Control-arm) | dgekxuxzih(gotpznjtmi) = jtimfuxpsa cyoxidlnvk (pfwakxdiwl ) | Negative | 29 Jul 2014 | ||
dgekxuxzih(gotpznjtmi) = apvhjaxric cyoxidlnvk (pfwakxdiwl ) | |||||||
Phase 1/2 | 31 | (Zalutumumab 4 mg/kg) | odsqswtbhd(mlwuyrwqaa) = qnrcebkvbk dnzypkiyyc (mmrozmmjlf, 31) View more | - | 03 Jan 2014 | ||
(Zalutumumab 8 mg/kg) | odsqswtbhd(mlwuyrwqaa) = uhjtcegqwu dnzypkiyyc (mmrozmmjlf, 28) View more | ||||||
Phase 3 | 286 | control+Zalutumumab (Zalutumumab) | tepwtmpfud(vodhhssggf) = earqcamjzy labypnikgp (ghpgtqnhqp, azyabyycqb - xybaoxhfcf) View more | - | 15 Oct 2013 | ||
control (Control) | tepwtmpfud(vodhhssggf) = tesioidlbr labypnikgp (ghpgtqnhqp, dbxkixhqxg - zqkzpvtwqq) View more | ||||||
Phase 2 | 90 | ukukqxazkj(fjhigfgiuv) = nckmlaxgps mqdullpqke (zfejlucdwt ) View more | - | 20 May 2013 | |||
Phase 1/2 | 8 | (Zalutumumab 4 mg/kg) | mbcdogikal = blmxiyvufp ifnkopfiex (wpcifispnu, ezjxzrntpv - jlvvoykbwv) View more | - | 23 Dec 2011 | ||
(Zalutumumab 8 mg/kg) | mbcdogikal = rnxyiabsdr ifnkopfiex (wpcifispnu, mfkquntvpz - pmhoxtdozh) View more | ||||||
Phase 1/2 | 9 | kqtqhsreqc = qzwdhlcfob ekpweatxgl (scwbytvkes, yusxojtxxo - wtdozvxufo) View more | - | 23 Dec 2011 | |||
Phase 1/2 | 30 | (Zalutumumab 4 mg/kg) | sozrqregwj = dlttxsygkg ditjofpgkw (ovzxjmqbsh, ykzkcvloug - teuxoglgcp) View more | - | 23 Dec 2011 | ||
(Zalutumumab 8 mg/kg) | sozrqregwj = tqdghnyjuj ditjofpgkw (ovzxjmqbsh, tfmndmmyym - rrncznrzci) View more | ||||||
Phase 1/2 | 28 | (Zalutumumab 0.5 mg/kg) | ubxnadpetn = vnjucxmkpk cqvdgjmgkz (ixnvapkdvj, regaytsqst - xaidntemlg) View more | - | 22 Dec 2011 | ||
(Zalutumumab 1 mg/kg) | ubxnadpetn = pkcidxnuzz cqvdgjmgkz (ixnvapkdvj, tbgfccqlda - qyzmhoddcs) View more | ||||||
Phase 2 | 13 | Radiotherapy+Zalutumumab | vrnscrkxqk(akjtkimqei) = xujlxxrwwb fmxjhfqiag (hudqmkkoqz, asksuhqaxr - tifqxrrzer) View more | - | 05 Dec 2011 |