Last update 21 Nov 2024

Citarinostat

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Citarinostat (USAN)
+ [2]
Target
Mechanism
HDAC6 inhibitors(Histone deacetylase 6 inhibitors)
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Structure

Molecular FormulaC24H26ClN5O3
InChIKeyVLIUIBXPEDFJRF-UHFFFAOYSA-N
CAS Registry1316215-12-9

External Link

KEGGWikiATCDrug Bank
D10918--

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Unresectable MelanomaPhase 2
US
30 Sep 2016
Advanced Malignant Solid NeoplasmPhase 2
US
22 Dec 2015
Multiple MyelomaPhase 2--
Solid tumorPhase 1
US
07 Jan 2022
Smoldering Multiple MyelomaPhase 1
US
07 Mar 2017
Smoldering Multiple MyelomaPhase 1
US
07 Mar 2017
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
18
(rddjmophgu) = wakcmheooy eyamwdvaqx (uadepdllgy )
-
01 Jan 2021
Phase 1
20
paclitaxel+citarinostat
(nfdjvsgthw) = citarinostat 360 mg/day daneethxwx (makllavfrz )
Positive
04 Jun 2018
Phase 1
40
(nubuzyjsuq) = 1 grade 4 thrombocytopenia at 360 mg fiveqpwbdj (zlnaascrec )
Positive
02 Dec 2016
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Approval

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Regulation

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