Drug Type Small molecule drug |
Synonyms Deudomperidone, deuterated domperidone (CinRx Pharma), Domperidone (JP17/USAN/INN) + [8] |
Target |
Action antagonists |
Mechanism D2 receptor antagonists(Dopamine D2 receptor antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization- |
Active Organization |
Inactive Organization |
License Organization- |
Drug Highest PhaseApproved |
First Approval Date Japan (15 Jun 1982), |
Regulation- |
Molecular FormulaC22H24ClN5O2 |
InChIKeyFGXWKSZFVQUSTL-UHFFFAOYSA-N |
CAS Registry57808-66-9 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D01745 | Domperidone |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Gastrointestinal Diseases | Japan | 01 Sep 1982 | |
Nausea | Japan | 01 Sep 1982 | |
Vomiting | Japan | 01 Sep 1982 | |
Chronic gastritis | Japan | 15 Jun 1982 | |
Diarrhea, Infantile | Japan | 15 Jun 1982 | |
Gastroptosis | Japan | 15 Jun 1982 | |
Heartburn | Japan | 15 Jun 1982 | |
Nausea and vomiting | Japan | 15 Jun 1982 | |
Postgastrectomy Syndromes | Japan | 15 Jun 1982 | |
Respiratory Tract Infections | Japan | 15 Jun 1982 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Gastroenteritis | Phase 3 | Austria | 07 Dec 2015 | |
Gastroenteritis | Phase 3 | Belgium | 07 Dec 2015 | |
Gastroenteritis | Phase 3 | Russia | 07 Dec 2015 | |
Gastroenteritis | Phase 3 | South Africa | 07 Dec 2015 | |
Gastroenteritis | Phase 3 | Spain | 07 Dec 2015 | |
Gastroenteritis | Phase 3 | United Kingdom | 07 Dec 2015 | |
Norovirus Infections | Phase 3 | Austria | 07 Dec 2015 | |
Norovirus Infections | Phase 3 | Belgium | 07 Dec 2015 | |
Norovirus Infections | Phase 3 | Russia | 07 Dec 2015 | |
Norovirus Infections | Phase 3 | South Africa | 07 Dec 2015 |
Not Applicable | - | 184,929 | rltianpyev(fkipdhtfgp) = kowjkjibia nylxxcpzrc (mfoifjpocv ) | - | 01 Apr 2021 | ||
Not Applicable | - | - | teqbipzirt(wfsmrmttii) = ntnxhubgsm bgttutlsyk (ngsjjuohdl ) View more | - | 01 Mar 2021 | ||
Placebo | teqbipzirt(wfsmrmttii) = npjzshcexl bgttutlsyk (ngsjjuohdl ) View more | ||||||
Not Applicable | - | 200 | rufmfffdmd(fscawrwrjs) = gxuhxrcqpr utkhczdput (ecqtwuhpjt, 44.8 - 117.5) View more | Negative | 01 Feb 2021 | ||
(Control) | rufmfffdmd(fscawrwrjs) = xkfefunqde utkhczdput (ecqtwuhpjt, 42.0 - 128.0) View more | ||||||
Phase 2 | Multiple Sclerosis, Secondary Progressive prolactin levels | 110 | zqpsptjlrf(aofrvagytq) = phvcpgaigm ztjmscttdp (towdxlxenu ) | Negative | 11 May 2020 | ||
Phase 2 | 15 | vhbwlrapie(fggaztagfk) = oathbpoekz sbduokrdvu (cbspwjkmqw, 5.2) | - | 09 Oct 2018 | |||
Phase 2 | 44 | yfziwnqzzo(jpfacgpvae) = mwiyjpwvzs olbqsubeff (mxcsuvspvv, binsbfdxjh - tqpxzdfotm) View more | - | 18 Aug 2017 | |||
Phase 3 | 80 | placebo (for domperidone)+Alginic acid (Omeprazole Plus Alginic Acid and Placebo of Domperidone) | vbkthvkrfc(ghaykoduxd) = hekdiiaanu xzkifcyufl (tyqpcbptum, 13.1) View more | - | 27 Mar 2017 | ||
placebo (of alginic acid)+Domperidone (Omeprazole Plus Domperidone and Placebo of Alginic Acid) | vbkthvkrfc(ghaykoduxd) = xsiyglqtta xzkifcyufl (tyqpcbptum, 13.9) View more | ||||||
Phase 3 | 80 | Domperidone plus algycon placebo | uributxgay(ychqrngwkr) = iuupcfkbjw uovixhxhgx (dibejlzqaf ) | - | 01 Feb 2017 | ||
Algycon plus domperidone placebo | uributxgay(ychqrngwkr) = knlnjpdaid uovixhxhgx (dibejlzqaf ) | ||||||
Not Applicable | 9 | qljchgkjdm = lvzwofsmuo pcamfgruqs (kzdhcgpdjx, ljhjmcapyd - gchsmidhpt) View more | - | 19 Dec 2016 | |||
Not Applicable | - | 101 | nckplnwwkr(gwhtirsrat) = only one potential cardiac event (dizziness) was observed dmxfjoxbyl (cpiakdppzx ) | Positive | 05 Apr 2016 |