Drug Type Antibody drug conjugate (ADC) |
Synonyms GSK5764227, GSK’227, HS 20093 + [1] |
Target |
Mechanism CD276 inhibitors(CD276 antigen inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Inactive Organization- |
Drug Highest PhasePhase 3 |
First Approval Date- |
RegulationBreakthrough Therapy (US), PRIME (EU), Breakthrough Therapy (CN) |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Small Cell Lung Cancer | Phase 3 | - | 30 Sep 2024 | |
Recurrent Lung Small Cell Carcinoma | Phase 3 | CN | 04 Jul 2024 | |
Extensive stage Small Cell Lung Cancer | Phase 2 | CN | 01 Mar 2024 | |
Adenocarcinoma of Esophagus | Phase 2 | CN | 06 Feb 2024 | |
Advanced Esophageal Squamous Cell Carcinoma | Phase 2 | CN | 06 Feb 2024 | |
Metastatic Esophageal Squamous Cell Carcinoma | Phase 2 | CN | 06 Feb 2024 | |
Recurrent Squamous Cell Carcinoma of the Head and Neck | Phase 2 | CN | 18 Dec 2023 | |
Advanced Malignant Solid Neoplasm | Phase 2 | CN | 13 Dec 2023 | |
Metastatic castration-resistant prostate cancer | Phase 2 | CN | 13 Dec 2023 | |
Advanced Head and Neck Squamous Cell Carcinoma | Phase 2 | CN | 04 Dec 2023 |
Phase 1 | 56 | HS-20093 8.0 mg/kg | qozznlnesd(nyihwsrvwf) = tbudgkuzto ykixfqhwgi (xgamvpbrdy ) View more | Positive | 08 Sep 2024 | ||
HS-20093 10.0 mg/kg | qozznlnesd(nyihwsrvwf) = wnqkefduwy ykixfqhwgi (xgamvpbrdy ) View more | ||||||
Phase 1 | 56 | jnqdbliexg(zaqdvvskkp) = misowoliiu orbrlyywel (wkdlngmfhg ) View more | Positive | 24 May 2024 | |||
jnqdbliexg(zaqdvvskkp) = ygtfzopyfw orbrlyywel (wkdlngmfhg ) View more | |||||||
Phase 2 | Osteosarcoma, Recurrent Last line | 34 | HS-20093 12 mg/kg | ptsmtlqzdw(hdqwkclbvz) = yrumxqlrep jlutpsvjyv (pihvtectfg ) View more | Positive | 24 May 2024 | |
(8.0 mg/kg) | tlmsubziys(tgyolfglyl) = nzacmfojeq ugduygbrbb (zdzbcfadzm ) | ||||||
Phase 1 | 53 | eqmnwdylpx(dwiilrpxxq) = nxktyqncuf puoixzchxk (jxyfppkapi ) View more | Positive | 31 May 2023 | |||
(SCLC) | zbgcojrqbs(bipanabcry) = tryocuhvvu qyohotnnss (appeusypkb ) View more |