Last update 08 Jan 2025

HS-20093

Overview

Basic Info

Drug Type
Antibody drug conjugate (ADC)
Synonyms
GSK5764227, GSK’227, HS 20093
+ [1]
Target
Mechanism
CD276 inhibitors(CD276 antigen inhibitors)
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
RegulationBreakthrough Therapy (US), PRIME (EU), Breakthrough Therapy (CN)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Small Cell Lung CancerPhase 3-30 Sep 2024
Recurrent Lung Small Cell CarcinomaPhase 3
CN
04 Jul 2024
Extensive stage Small Cell Lung CancerPhase 2
CN
01 Mar 2024
Adenocarcinoma of EsophagusPhase 2
CN
06 Feb 2024
Advanced Esophageal Squamous Cell CarcinomaPhase 2
CN
06 Feb 2024
Metastatic Esophageal Squamous Cell CarcinomaPhase 2
CN
06 Feb 2024
Recurrent Squamous Cell Carcinoma of the Head and NeckPhase 2
CN
18 Dec 2023
Advanced Malignant Solid NeoplasmPhase 2
CN
13 Dec 2023
Metastatic castration-resistant prostate cancerPhase 2
CN
13 Dec 2023
Advanced Head and Neck Squamous Cell CarcinomaPhase 2
CN
04 Dec 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
56
HS-20093 8.0 mg/kg
qozznlnesd(nyihwsrvwf) = tbudgkuzto ykixfqhwgi (xgamvpbrdy )
Positive
08 Sep 2024
HS-20093 10.0 mg/kg
qozznlnesd(nyihwsrvwf) = wnqkefduwy ykixfqhwgi (xgamvpbrdy )
Phase 1
56
jnqdbliexg(zaqdvvskkp) = misowoliiu orbrlyywel (wkdlngmfhg )
Positive
24 May 2024
jnqdbliexg(zaqdvvskkp) = ygtfzopyfw orbrlyywel (wkdlngmfhg )
Phase 2
34
HS-20093 12 mg/kg
ptsmtlqzdw(hdqwkclbvz) = yrumxqlrep jlutpsvjyv (pihvtectfg )
Positive
24 May 2024
(8.0 mg/kg)
tlmsubziys(tgyolfglyl) = nzacmfojeq ugduygbrbb (zdzbcfadzm )
Phase 1
53
eqmnwdylpx(dwiilrpxxq) = nxktyqncuf puoixzchxk (jxyfppkapi )
Positive
31 May 2023
(SCLC)
zbgcojrqbs(bipanabcry) = tryocuhvvu qyohotnnss (appeusypkb )
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Regulation

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